Publications

Publications

Publications

The Evolving Role of ctDNA in Merkel Cell Carcinoma: Challenges and Opportunities

This Perspective on the Science piece, published in the Journal of Cutaneous Oncology we discuss the evolving role of circulating tumor DNA (ctDNA) in the management of Merkel Cell Carcinoma, highlighting findings from a recent multicenter study and insights from a multi-institutional Journal Club. Key opportunities and challenges related to ctDNA’s use in surveillance and treatment decision-making are explored.

David Michael Miller, MD, PhD, Vernon Keith Sondak MD, Sunandana Chandra MD, Kenneth Y Tsai, Howard Lane Kaufman, Sameer Gupta MD, Isaac Brownell, Yoshine Saito, Ann W. Silk, Manisha Thakuria, Paul Nghiem MD, PhD

Immunotherapy for Advanced Conjunctival Squamous Cell Carcinoma: Treatment Failures

In this article, published in Ophthalmic Plastic and Reconstructive Surgery, we present a cohort study of patients treated with immunotherapy for advanced conjunctival SCC.

Azad Amee D, Zhang Jia Jia, Emerick Kevin S, Shalhout Sophia Z, Kaufman Howard L, Miller David M, Lee Nahyoung G, Yoon Michael K, Freitag Suzanne, Stagner Anna M, Wolkow Natalie

The Evolving Treatment Landscape for CSCC

This article, published in Archives of Dermatological Research, examines the evolving role of immunotherapy and dermatologists in CSCC treatment.

David Michael Miller, MD, PhD

Comparing First-Line Immunotherapy in Advanced Melanoma: No Clear Winner?

In this Perspective on Science piece, published in the Journal of Cutaneous Oncology, we reflect on the indirect treatment comparison analysis between RELATIVITY-047 and CheckMate 067 trial data.

Yoshine Saito, David Michael Miller, Isaac Brownell

Should Ipilimumab Be the New “Standard” for Refractory MCC?

In this editorial, published in the Journal of Cutaneous Oncology, we discuss the role of ipilimumab in anti-PD-1 refractory Merkel cell carcinoma. This topic was presented at the Third International Symposium for MCC in Houston, Texas on May 4th 2024.

David Michael Miller, MD, PhD

Tumor-Infiltrating Lymphocyte Therapy Receives FDA Approval

In this editorial, published in the Journal of Cutaneous Oncology, we reflect on the recent approval of the first cellular therapy for melanoma.

Jennifer Strong, David Michael Miller, MD, PhD, Isaac Brownell, MD, PhD

Neoadjuvant-Intent Immunotherapy in Advanced, Resectable Cutaneous Squamous Cell Carcinoma

In this article, published in JAMA Otolaryngology-Head & Neck Surgery, we present a cohort study of patients treated with neoadjuvant cemiplimab or pembrolizumab for advanced cSCC

Kim EY, Ruiz ES, DeSimone MS, Shalhout SZ, Hanna GJ, Miller DM, Schmults C, Rettig EM, Foreman RK, Sethi R, Thakuria M, Silk Ann W

The Prognostic Value of the Merkel Cell Polyomavirus Serum Antibody Test: A Dual Institutional Observational Study

In this preprint, subsequently published in Cancer, we evaluate the prognostic value of the Merkel Cell Polyomavirus serum antibody test

David M. Miller MD PhD, Sophia Z. Shalhout PhD, Kayla Wright, Matt Miller, Howard L. Kaufman MD5, Kevin S. Emerick MD, Harrison Reeder PhD, Ann W. Silk MD, Manisha Thakuria MD

Perspectives on Medical Aid in Dying: A Multifaceted Ethical Discussion

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the complex ethical considerations surrounding Medical Aid in Dying, integrating insights from a recent multi-institutional journal club discussion.

David Michael Miller, MD, PhD, Isaac Brownell, MD, PhD, Vatche Tchekmedyian, MD, Fishal A. Patel, MD, Howard Lane Kaufman, MD, Kevin Scott Emerick, MD

Imaging Surveillance for Stage III Melanoma: Should We Be Stalkers or Casual Observers?

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the role of surveillance imaging for patients with high-risk melanoma.

Kevin Scott Emerick, MD, David Michael Miller, MD, PhD

A Closer Look: Evaluating Mohs Surgery’s Role in the Treatment of Invasive Melanoma of the Head and Neck

In this Perspectives on the Science piece, we reflect on the implications of the recently conducted multicenter study on the treatment of invasive head and neck melanoma using Mohs micrographic surgery.

Ching, Lauren, Strong, Jennifer, Lee, Truelian, Kaufman, Howard L., Emerick, Kevin S., Kim, Emily Y., Patel, Vishal A., Brownell, Isaac, Singh, Kritika, Neel, Victor A., Miller, David Michael, Gupta, Sameer

Adjuvant anti-PD-1 for Merkel Cell Carcinoma: Ready for the Clinic?

In this Perspectives on the Science piece we reflect on the recently published ADMEC-O trial.

David M. Miller, Jennifer Strong, Kevin S. Emerick, Sameer Gupta, Ann W. Silk, Isaac Brownell

To Screen or Not To Screen, That is the Question

In this Perspectives on the Science piece we reflect on the impact of the recent USPSTF recommendation statement on skin cancer screening.

Truelian Lee, David M. Miller, Howard L. Kaufman, Kevin S. Emerick, Sameer Gupta, Laura K. Ferris

Immunotherapy and Cardiovascular Health - A Cause for Concern?

In this Perspectives on the Science piece we reflect on the impact of ‘Association Between Immune Checkpoint Inhibitors With Cardiovascular Events and Atherosclerotic Plaque’ by Drobni et al.

David M. Miller, Laura K. Ferris, Sameer Gupta, Isaac Brownell, Sophia Z. Shalhout

Perioperative Immunotherapy for High-Risk Resectable Melanoma - A New Standard?

In this Perspectives on the Science piece we reflect on the impact of the recently published SWOG S1801 trial.

Serena Vilasi, David M. Miller, Howard L. Kaufman, Kevin S. Emerick, Sophia Z. Shalhout, Emily Y Kim, Vishal A. Patel, Khalid Garmen, Sameer Gupta, Isaac Brownell

Skin Cancer Chemoprevention for Transplant Recipients - The Search Continues

In this Perspectives on the Science piece, we reflect on the impact of the recently published ONTRANS trial.

Howard L. Kaufman, Vishal A. Patel, Sophia Z. Shalhout, Sameer Gupta, Sonia Cohen, Isaac Brownell, David M. Miller

Surgical Factors Affecting Regionally Metastatic Cutaneous Squamous Cell Carcinoma to the Parotid Gland

Understanding the impact of surgical treatment on regionally metastatic cutaneous squamous cell carcinoma (cSCC) is important as treatment paradigms shift with the introduction of immune checkpoint inhibitors. Herein, we aim to describe surgical impact on outcomes for regionally metastatic cSCC

Vishwanatha M. Rao, Allen L. Feng, Daniel G. Deschler, Howard Kaufman; Derrick T. Lin, David M. Miller, Jeremy D. Richmon, Sophia Z. Shalhout, Mark A. Varvares, Kevin S. Emerick

Lacking Overall IMspiration for Triplet Therapy in Melanoma? A Review of the Interim Analysis of IMspire150.

In this Perspectives on the Science piece, we reflect on the impact of the recently published article by Ascierto et al. in Lancet Oncology that provides interim results from IMspire150.

David M. Miller, Kevin S. Emerick, Vishal A. Patel, Sonia Cohen, Isaac Brownell, Donald P. Lawrence

Targeting TBK1 to overcome resistance to cancer immunotherapy

We demonstrate that targeting TBK1 is a novel and effective strategy to overcome resistance to cancer immunotherapy.

Sun Y, Revach OY, Anderson S, Kessler EA, Wolfe CH, Jenney A, Mills CE, Robitschek EJ, Davis TGR, Kim S, Fu A, Ma X, Gwee J, Tiwari P, Du PP, Sindurakar P, Tian J, Mehta A, Schneider AM, Yizhak K, Sade-Feldman M, LaSalle T, Sharova T, Xie H, Liu S, Michaud WA, Saad-Beretta R, Yates KB, Iracheta-Vellve A, Spetz JKE, Qin X, Sarosiek KA, Zhang G, Kim JW, Su MY, Cicerchia AM, Rasmussen MQ, Klempner SJ, Juric D, Pai SI, Miller DM, Giobbie-Hurder A, Chen JH, Pelka K, Frederick DT, Stinson S, Ivanova E, Aref AR, Paweletz CP, Barbie DA, Sen DR, Fisher DE, Corcoran RB, Hacohen N, Sorger PK, Flaherty KT, Boland GM, Manguso RT, Jenkins RW

Therapy with oncolytic viruses: progress and challenges

We review the available data and provide guidance on optimizing the use of oncolytic viruses in clinical practice.

Sophia Z. Shalhout, David M. Miller, Kevin S. Emerick, Howard L. Kaufman

Tumor-Infiltrating Lymphocyte Therapy for Advanced Melanoma: Ready for Prime Time?

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the impact of the recently published article “Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma”.

Emily Y Kim, Sophia Z. Shalhout, Howard L. Kaufman, Kevin S. Emerick, Vishal A. Patel, Khalid Garmen, Isaac Brownell, David M. Miller

StoryboardR - An R Package and Shiny Application Designed to Visualize Real-World Data From Clinical Patient Registries

We created StoryboardR, an R package and Shiny application facilitates the data visualization of real-world data from tumor registries captured in REDCap^®.

David M. Miller, Sophia Z. Shalhout

Neoadjuvant Nivo/Rela for Resectable Melanoma

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the impact of the recently published article Neoadjuvant relatlimab and nivolumab in resectable melanoma.

David M. Miller, Howard L. Kaufman, Kevin S. Emerick, Justine V. Cohen, Emily Y Kim, Sophia Z. Shalhout

Ipi/Nivo for Advanced MCC

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the impact of the recently published article “Combined Nivolumab and Ipilimumab with or without Stereotactic Body Radiation Therapy for Advanced Merkel cell carcinoma - A Randomised, Open Label, Phase 2 Trial”.

Sophia Z. Shalhout, Justine V. Cohen, Khalid Garmen, Emily Y Kim, Sonia Cohen, David M. Miller

Neoadjuvant ICI for Resectable CSCC

In this Perspectives on the Science piece, published in the Journal of Cutaneous Oncology, we reflect on the impact of the recently published article Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma.

David M. Miller, Vishal A. Patel, Justine V. Cohen, Khalid Garmen, Sophia Z. Shalhout