Clinical & Translational Investigators in Skin Cancer

Ongoing Projects, Research and Efforts

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Clinical Educator

Participating in the education of tomorrow’s clinicians

Real World Data Analysis

Optimizing Real World Data Collection

Clinical Trials for Skin Cancer

Investigating novel therapies for patients with advanced skin cancer

Biomarkers of Response and Resistance to Cancer Therapy

Investigating why patients do or do not respond to cancer therapies

Data Science Tool Development

Developing Data Science tools to facilitate clinical and translational research

Evolving Landscape of Regulatory Medicine

Evaluating the evolving landscape of regulatory medicine in Cutaneous Oncology and Dermatology

Merkel Cell Carcinoma Patient Registry

Developing a multi-institutional Patient Registry.

Meet the Team

Principal Investigator

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David Michael Miller

Medical Oncologist and Dermatologist

Clinical And Translational Research, Advanced Skin Cancer, Data Science, R

Fellows

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Sophia Shalhout

Cutaneous Oncology Research Fellow

Clinical and Biomedical Informatics, Immuno-oncology/Cutaneous Oncology, R/Data Science

Students

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Farees Saqlain

Medical Student

Clinical And Translational Research, Merkel Cell Carcinoma, Squamous Cell Carcinoma

Researchers

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Kayla Wright

Clinical Research Assistant

Biomedical Research, Photography

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Matthew Miller

Clinical Research Assistant

Biomedical Research

Publications

Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma

We present a prosepective study of neoadjuvant cemiplimab in high-risk resectable CSCC.

StoryboardR - An R Package and Shiny Application Designed to Visualize Real-World Data From Clinical Patient Registries

We created StoryboardR, an R package and Shiny application facilitates the data visualization of real-world data from tumor registries …

BodyMapR - An R Package and Shiny Application Designed to Generate Anatomical Visualizations of Cancer Lesions

We present BodyMapR, an R package & Shiny application that generates anatomical visualizations of cancer lesions from REDCap.

Evaluation of clinical characteristics and pre-biopsy impressions of primary Merkel cell carcinoma of the skin

A review of prebiopsy clinical DDx of primary cutaneous MCC lesions from a recent, single-institution 5 year cohort.

Recent & Upcoming Talks

Cases in Basal Cell Carcinoma: Fostering Interdisciplinary Care

Pearls in the management of Basal Cell Carcinoma

Immunotherapeutic Strategies in Skin Cancer

Primer on Immunotherapeutic Strategies in Skin Cancer

Recent Posts

Perspectives on the Science: Ipi/Nivo for Advanced MCC

We provide a commentary on the recent Lancet Oncology article on Ipi/Nivo advanced MCC.

Perspectives on the Science: Neoadjuvant Cemiplimab for High-Risk CSCC

We provide a commentary on the recent NEJM article on neoadjuvant cemiplimab for advanced CSCC.

Optimizing Real-World Data Collection: The Lesion Information Electronic Data Capture Instrument

We publish the data dictionary for our Lesion Information data collection instrument

Data Quality Improvement in Cancer Registries- Error-Injection Tests

A proposed workflow for monitoring completion of retrospective records in a patient registry hosted on REDCap

Optimizing Real-World Data Collection: Genomics Electronic Data Capture Instrument

We publish the data dictionary for our genomics data collection instrument

FlexDashboards for Clinical and Translational Research

A monograph on how to create Dashboards using R via a package called flexdashboard

A REDCap-to-R Pipeline for Interactive Body Map Visualizations in Cutaneous Oncology

A data science tool for interactive visualizations of skin cancer lesions

Communicating CT Research via Website Development with R

This working document is a rough user guide on how to create a website using R via a package called blogdown

Optimizing Real-World Data Collection: Clinical Genomics

Facilitate capture of real-world next-generation genomic data

Reference Management in RMarkdown

Integrate your EndNote library into RMarkdown

Software

StoryboardR

A Shiny App to visualize the patient journey from registry data

BodyMapR

A Shiny app that generates anatomical visualizations of cancer lesions from structured data

FDA Approvals in Skin Cancer - A Shiny App

A Shiny App to visualize the FDA approved therapies for skin cancer

GENETEX

A Shiny App to perform NLP on clinicogenomic data

Generalizable EHR Labs Abstraction (eLAB) Pipeline

A pipeline to extract laboratory data from Epic and integrate into a structured research database

Past and Current Funding

ECOG ACRIN Paul Carbone, MD Fellowship Award

A Novel JAK1 Inhibitor to Overcome BRAF/MEK Inhibitor Resistance in V600-BRAF Mutant Melanoma

American Skin Association Research Grant

JAK1 Inhibition to Overcome BRAF/MEK Inhibitor Resistance in V600-BRAF Mutant Melanoma

American Diabetes Association Physician Scientist Training Award

Umbilical cord blood stem cells as therapy for Diabetes Mellitus

Support Cancer Research

If you are interested in supporting our research please visit our Donation page at Massachusetts General Hospital by clicking here.

Contact

Clinical Matters:

For clinical questions, please contact the MGH Cancer Center
Telephone: 617-724-5197
Fax: 617-643-1740

Lab Related Matters

The below contact information is for The Miller Lab related matters

Email

  • 617-726-2667
  • 15 Parkman Street, Boston, MA, 02114, United States
  • Enter Bartlett Hall, to Basement, Room 132
  • DM Me