Clinical & Translational Investigators in Skin Cancer

Ongoing Projects, Research and Efforts


Clinical Educator

Participating in the education of tomorrow’s clinicians

Real World Data Analysis

Optimizing Real World Data Collection

Clinical Trials for Skin Cancer

Investigating novel therapies for patients with advanced skin cancer

Biomarkers of Response and Resistance to Cancer Therapy

Investigating why patients do or do not respond to cancer therapies

Data Science Tool Development

Developing Data Science tools to facilitate clinical and translational research

Evolving Landscape of Regulatory Medicine

Evaluating the evolving landscape of regulatory medicine in Cutaneous Oncology and Dermatology

Merkel Cell Carcinoma Patient Registry

Developing a multi-institutional Patient Registry.

Meet the Team

Principal Investigator


David Michael Miller

Medical Oncologist and Dermatologist

Clinical And Translational Research, Advanced Skin Cancer, Data Science, R



Sophia Shalhout

Cutaneous Oncology Research Fellow

Clinical and Biomedical Informatics, Immuno-oncology/Cutaneous Oncology, R/Data Science



Farees Saqlain

Medical Student

Clinical And Translational Research, Merkel Cell Carcinoma, Squamous Cell Carcinoma



Kayla Wright

Clinical Research Assistant

Biomedical Research, Photography


Matthew Miller

Clinical Research Assistant

Biomedical Research

Recent & Upcoming Talks

Merkel Cell Carcinoma - Current Concepts in Diagnosis and Management

Pearls on the current concepts in diagnosis and management of MCC

GENETEX - an NLP R Package for Text Mining Genomic Reports

Immune Checkpoint Inhibitor for Cutaneous Squamous Cell Carcinoma

Pearls for the Management of Advanced CSCC

mGODS - Monoclonal Gammopathies Of Dermatological Significance

Pearls for working up monclonal gammopathies in setting of dermatological disease

MCC Patient Registry - Lessons Learned, Future Directions

MCC Patient Registry - Lessons Learned on Data Capture

Work Up and Management of Cutaneous Melanoma

Pearls for the work up and management of cutaneous melanoma

Project Data Sphere & MCC patient Registry- From Promise to Prototype to Patient

We provide updates and future directions of the PDS-GOBDA MCC Registry

Recent Posts

Data Quality Improvement in Cancer Registries- Error-Injection Tests

A proposed workflow for monitoring completion of retrospective records in a patient registry hosted on REDCap

Optimizing Real-World Data Collection: Genomics Electronic Data Capture Instrument

We publish the data dictionary for our genomics data collection instrument

FlexDashboards for Clinical and Translational Research

A monograph on how to create Dashboards using R via a package called flexdashboard

A REDCap-to-R Pipeline for Interactive Body Map Visualizations in Cutaneous Oncology

A data science tool for interactive visualizations of skin cancer lesions

Communicating CT Research via Website Development with R

This working document is a rough user guide on how to create a website using R via a package called blogdown


GENETEX - A GENomics Report TEXt Mining R Package and Shiny Application Designed to Capture Real-World Clinico-Genomic Data

We created GENETEX, an R package and Shiny application for text mining genomic reports from EHR and direct import into REDCap®.

Immune Checkpoint Inhibition in Marjolin Ulcer - A Case Series

We provide a case series in the Journal of Immunotherapy of response to anti-PD1 therapy in Marjolin Ulcer.

Commentary on Surgical Margins in MCC

We provide commentary on a recent publication in JAMA Derm on margins in MCC.

Microsatellitosis in Merkel cell carcinoma - a staging quandary

We provide an analysis in the Dermatology Online Journal of microsatellitosis in a cohort of MCC patients.

Past and Current Funding

ECOG ACRIN Paul Carbone, MD Fellowship Award

A Novel JAK1 Inhibitor to Overcome BRAF/MEK Inhibitor Resistance in V600-BRAF Mutant Melanoma

American Skin Association Research Grant

JAK1 Inhibition to Overcome BRAF/MEK Inhibitor Resistance in V600-BRAF Mutant Melanoma

American Diabetes Association Physician Scientist Training Award

Umbilical cord blood stem cells as therapy for Diabetes Mellitus


Clinical Matters:

For clinical questions, please contact the MGH Cancer Center
Telephone: 617-724-5197
Fax: 617-643-1740

Lab Related Matters

The below contact information is for The Miller Lab related matters


  • 617-726-2667
  • 15 Parkman Street, Boston, MA, 02114, United States
  • Enter Bartlett Hall, to Basement, Room 132
  • DM Me