Overview

• In this lecture we review the most common dermatoses that result from monoclonal gammopathies. The lecture also introduces the term mGODS: Monoclonal Gammopathies of Dermatological Significance as an umbrella term that captures diseases such as Cutaneous Amyloidoses, Scleromyxedema, Acquired Cutis Laxa, Mixed Cryoglobulinemia, Nodular Amyloidoses, PEOMS syndrome, Necrobiotic Xanthogranuloma, Schnitzler’s Syndrome etc.

Learning Objectives

• Provide an overview of plasma cell dyscrasias
• Introduce the concept of mGODS
• Review techniques to detect and identify monoclonal roteins
• Revew how to work up paraproteins
• Provide an overview of MGUS