Dermatology

Pearls for the management of advanced melanoma

This lecture was filmed and will be part of the HMS Cancer Biology and Therapeutics Global Education Lecture Overview & Learning Objectives Understand the role of diagnostic imaging and sentinel lymph node biopsy in the work up of MCC Recognize the use of the Merkel cell polyoma virus serum antibody test in clinical practice Discuss recently approved therapeutic strategies in MCC, including the use of ICIs as primary treatment, as well as emerging strategies in the neo-adjuvant and adjuvant setting

We evaluate the fragility of pivotal trials used to support FDA approval in Plaque Psoriasis.

Overview & Learning Objectives This Lecture has the following learning objectives Brief overview of Epidemiology of Cutaneous Squamous Cell Carcinoma (CSCC) Review Pathophysiology of CSCC Review Staging Review Prognosis of Advanced CSCC (AdVCSCC) Review Work Up of CSCC Discuss recently approved therapeutic strategies in CSCC, including the use of Immunce Checkpoint Inhibitors (ICIs) as primary treatment, as well as emerging strategies in the neo-adjuvant and adjuvant setting We will use the following cases as guides throughout the lecture These are fictional cases, any apparent relationship to actual patients is purely coincidental.

Overview & Learning Objectives The objective of this lecture is to provide an overview of salient intersections between Dermatology and Hematology We will use the following cases as guides throughout the lecture These are a fictional cases. The first case is loosely based off one that was presented at a Clinical-Pathologic Case Conference when I was a House Officer at Brigham and Women’s Hospital. I have changed several aspects of the case to de-identify it, though the medical principles of the case remain intact.

We present a case of Acquired Cutis Laxa associated with Monocloncal Gammopathy of Monoclonal Significance.

Slides for NEDS Updates in MCC