Optimizing Real-World Data Collection: The Lesion Information Electronic Data Capture Instrument

Article type: Application Note

Authors: David M. Miller*1,2,3 MD PhD, Farees Saqlain3, Sophia Z. Shalhout1,3 PhD

1Department of Medicine, Division of Hematology/Oncology, 2Department of Dermatology, Massachusetts General Hospital, and 3Harvard Medical School, Boston, MA

*Corresponding author: David M. Miller MD PhD
Massachusetts General Hospital
15 Parkman St. Room 132
Boston MA 02114

Funding sources: The Harvard Cancer Center Merkel Cell Carcinoma patient registry is supported by grants from Project Data Sphere, ECOG-ACRIN and the American Skin Association.

Conflicts of interest: None

Keywords: real-world data, clinical informatics, patient-level data

Acknowledgments: The authors would like to thank the members of the Project Data Sphere Merkel Cell Carcinoma Patient Registry Task Force for their contributions to the development of a multi-institutional registry. We would also like to thank Kayla Wright for her feedback on the various versions of the Lesion Information Instrument. Her input lead to an improved user interface and user experience.

Abbreviations: CSV: comma separated values, DCS: data capture specialist, EDC: electronic data capture, EHR: electronic health record, LII: lesion information instrument, MCC: Merkel cell carcinoma, NED: no evidence of disease, REDCap: Research Electronic Data Capture, RWD: real-world data, UI: user interface, UX: user experience

ABSTRACT

Objectives: To develop a data collection instrument designed to capture patient level clinical tumor characteristics obtained in the real-world setting.
Materials and Methods: The Lesion Information Instrument was created as a csv file and is formatted to be used as a data collection form as part of a REDCap® project.
Results: We present a REDCAp®-based data collection instrument that captures over 150 data elements pertaining to clinical tumor characteristics.
Conclusions: The Lesion Information Instrument is a freely-available data collection form that can be used to improve the understanding of the natural history of the disease being studied. Its extensible structure allows it to be incorporated into a variety of REDCAp® projects and clinical informatic pipelines.

Objectives

Real world data (RWD), healthcare data derived from heterogeneous patient cohorts, is a critical source of information that can help guide medical decision making in areas of uncertainty. Structured data capture of patient-level data is essential to maximize the utility of RWD. While the 2009 Health Information Technology for Economic and Clinical Health Act (HITECH) improved the utilization of health information technologies,1 significant limitations to the collection of RWD remain. Modern EHR systems contain large volumes of unstructured data, limiting our ability to make patient-level data actionable as RWD. Therefore, structured data capture of clinically relevant variables is essential to maximize advances in HIT.

The number of clinically relevant variables available for collection by investigators increases on a near quotidian basis. In oncology, few domains rival clinical tumor characteristics (e.g. type of lesion (primary vs. metastasis), date of detection, location, appearance, size, response to treatment) in importance. A variety of software exist to facilitate the development of customizable data collection instruments (DCIs) to capture patient-level data, such as clinical tumor characteristics. One such platform, the Research Electronic Data Capture system REDCap®2,3, is currently accessed by over 1.8 million end-users.4 REDCap® DCIs can be developed with an in-platform online designer or externally by creating comma separated value (csv) files. Distinct DCIs, with modular capability, can be integrated into a larger REDCap® project to capture patient-level data across a variety of domains. For example, we have recently published a DCI entitled the Genomics Instrument, which facilitates the collection of clinico-genomic data (CGD)5. This DCI has been incorporated by the Project Data Sphere led Merkel Cell Carcinoma (MCC) Patient Registry6 in order to capture CGD.

Unfortunately, the development of comprehensive data collection instruments that are approachable by end users with a variety of technical backgrounds and skill levels (e.g. clinical research associates, graduate students, medical professionals with doctorate degrees) are time consuming to construct. Particular attention to the user experience (UX) and user interface (UI) are needed and often require extensive use of software engineering techniques such as piping, field embedding and branching logic. Knowledge and experience of these features can be a barrier to entry for clinical research teams and can prolong time-to-insight from RWD. Therefore, the development of a freely-available, modular, comprehensive, yet easy-to-use, data collection instruments dedicated to the capture of clinical tumor characteristics is needed.

Here, we present the Lesion Information Instrument (LII), a modular, repeating REDCap®-based data collection instruments designed to enable structured data collection of cancer lesion characteristics.

Methods

The LII was developed as a csv file using Microsoft Excel7. The data dictionary for the LII (Table 1) is available upon request.

Click to View Table 1: Lesion Information Instrument Data Dictionary
Variable / Field Name Form Name Section Header Field Type Field Label Choices, Calculations, OR Slider Labels Field Note Text Validation Type OR Show Slider Number Text Validation Min Text Validation Max Identifier? Branching Logic (Show field only if…) Required Field? Custom Alignment Question Number (surveys only) Matrix Group Name Matrix Ranking? Field Annotation
record_id lesion_information text Record ID NA NA NA NA NA NA NA
les_det_hdr lesion_information descriptive <div style=“background-color:lightyellow;”>Lesion Detection</div> NA NA NA NA NA NA NA
lesion_tag lesion_information text <div class=“rich-text-field-label”><p>Lesion [current-instance] Tag</p></div> Enter a short phrase to reference this Lesion instance throughout this record. Ex. “left knee papule” or “right axillary nodal mets”. NA NA NA NA NA NA NA WORDLIMIT? = 12
tum_id_dtc_img_hdr lesion_information descriptive <div style=“margin-left: 20px; padding-left: 5px; border-left: 5px solid red; background-color:Wheat;”>Mark presence of Lesion [current-instance] in the corresponding instance of the Imaging Instrument.</div> NA NA NA [tum_id_dtc_method] = ‘1’ NA NA NA NA
tum_dtctn_dt lesion_information text <div style=“margin-left: 0px;”>Date of First Documentation (first complete date noted in chart) (tum_dtctn_dt)</div> The Date of First Documentation refers to the first date of a clinical encounter at which the lesion was first clinically appreciated, whether by physical exam or radiographic imaging documenting the lesion. date_mdy NA NA NA NA NA NA NA
tum_dtctn_dt_approx lesion_information checkbox <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Is this date an approximation? <br />(tum_dtctn_dt_approx)</p></div> 1, Yes In some circumstances the precise date of detection is not known, if that is the case, check this box and put in the first of the month NA NA NA NA NA NA NA
tum_id_dtc_method lesion_information dropdown <div class=“rich-text-field-label”><p>Modality associated with First Documentation of Lesion <br />(tum_id_dtc_method)</p></div> 0, Physical Exam (0) | 1, Imaging (1) | 2, Histology (2) | 98, Unknown/Not Reported (98) An example of histologic first detection of a lesion would be sentinel biopsy revealing micrometastases. autocomplete NA NA NA NA NA NA NA
tum_histo_conf_yn lesion_information dropdown Was this lesion confirmed histologically? (tum_histo_conf_yn) 0, No, histology/pathology never performed (0) | 1, Yes, histology confirmed MCC (1) | 2, Histology performed and lesion was not consistent with MCC (2) autocomplete NA NA NA NA NA NA NA
tum_histo_date lesion_information text <p style=“margin-left: 20px;”>Date of histological examination<br />(tum_histo_date)</p> date_mdy NA NA NA [tum_histo_conf_yn] = 1 OR [tum_histo_conf_yn] = 2 NA NA NA NA
les_clindesc_hdr lesion_information descriptive <div style=“background-color:lightyellow;”>Clinical Description of Lesion</div> NA NA NA NA NA NA NA
tum_type lesion_information dropdown Type of Lesion [current-instance] (tum_type) 1, Primary Cutaneous Tumor (1) | 2, Metastasis (2) | 3, MCC of Unknown Primary (non-cutaneous lesion at initial presentation) (3) | 4, Local Recurrence (4) | 5, Histologically not consistent with MCC (5) | 6, Unclear Etiology/Not Confirmed as MCC (6) | 98, Unknown/Not Reported (98) autocomplete NA NA NA NA NA NA NA
tum_loc lesion_information dropdown Location of Lesion (tum_loc) 1, Skin/Muscle/Soft Tissue (1) | 2, Viscera (2) | 3, Lymphatic (3) | 4, CNS/Brain (4) | 5, Bone (5) | 6, Ocular (6) | 7, Mucosa (7) | 8, Peritoneum/Retroperitoneum (8) | 9, Bodily fluids (eg ascites, pleural effusions) (9) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA NA NA NA NA
met_type lesion_information dropdown <div style=“margin-left: 20px;”>Type of Metastases (met_type)</div> 1, Satellite or In-transit (1) | 2, Regional Lymph Node Basin (2) | 3, Distant (3) | 98, Unknown/Not Reported (98) | 99, Other (99) If this is a new metastases for a patient initially diagnosed with an MCC of unknown primary, the category of mestastasis (satellite or in-transit, regional lymph node basin, or distant) is in geographic reference to the presenting lesion. autocomplete NA NA NA [tum_type]=2 NA NA NA NA
met_type_other lesion_information text <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Type of Metastases - Other</p></div> NA NA NA [met_type] = 99 NA NA NA NA
tum_id_header lesion_information descriptive <div style=“padding-left: 5px; margin-left: 20px; border-left: 5px solid red; background-color:Wheat;”>If multiple tumors are discovered concomitantly within one organ or lymph node basin, capture them in a single instance of the “Lesion” instrument. Groups of tumors arising at separate time points within the same organ or lymph node basin must be captured in separate instances.</div> NA NA NA [tum_type]=2 OR [tum_type]=3 NA NA NA NA
tum_num lesion_information dropdown <div style=“margin-left: 20px;”>Number of tumors/lesions captured by Lesion [current-instance] (tum_num)</div> 1, One (1) | 2, Multiple (2) | 98, Unknown/Not Reported (98) autocomplete NA NA NA [tum_type]=2 OR [tum_type]=3 OR [tum_type]=4 NA NA NA NA
tum_num_detail lesion_information text <div class=“rich-text-field-label”><p style=“margin-left: 40px;”>Number of Tumors/Lesions </p> <p style=“margin-left: 40px;”>(tum_num_detail)</p></div> NA NA NA [tum_num]=2 NA NA NA NA
tum_num_cat lesion_information dropdown <div class=“rich-text-field-label”><p style=“margin-left: 40px;”>Number of Tumors/Lesions </p> <p style=“margin-left: 40px;”>(tum_num_cat)</p></div> 1, 2-10 | 2, 11-20 | 3, > 20 autocomplete NA NA NA [tum_num]=2 NA NA NA NA
tum_loc_laterality lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Laterality (tum_loc_laterality)</div> 1, Right (1) | 2, Left (2) | 3, Midline (3) | 4, Not applicable (4) | 98, Unknown/Not Reported (98) | 99, Other (99) This is to designate right and left extremities, but also if a lesion is on the right side of the chest, for example or in the middle of the chest autocomplete NA NA NA [tum_loc]=1 OR [tum_loc] = 2 NA NA NA NA
tum_loc_ant_post lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Anterior vs. Posterior (tum_loc_ant_post)</div> 1, Anterior (1) | 2, Posterior (2) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc]=1 NA NA NA NA
tum_loc_med_lat lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Medial vs. Lateral (tum_loc_med_lat)</div> 1, Medial (1) | 2, Lateral (2) | 3, Midline/Center/Middle (3) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc] = “1” AND [tum_loc_laterality] != “3” NA NA NA NA
tum_loc_skin lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Skin/Muscle/Soft Tissue (tum_loc_skin)</div> 1, Head/Neck (1) | 2, Chest (2) | 3, Abdomen (3) | 4, Back (4) | 5, Upper Extremity (5) | 6, Genitalia (6) | 7, Buttocks (7) | 8, Lower Extremity (8) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc]=1 NA NA NA NA
tum_loc_head lesion_information dropdown <div style=“margin-left: 40px;”>Lesion Location - Head/Neck (tum_loc_head)</div> 1, Scalp (1) | 2, Forehead (2) | 3, Eyelid (3) | 4, Nose (4) | 5, Cheek (5) | 6, Lip (6) | 7, Chin (7) | 8, Neck (8) | 9, Ear (9) | 10, Eyebrow (10) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc_skin]=1 NA NA NA NA
tum_loc_lip lesion_information dropdown <div style=“margin-left: 60px;”>Source Location - Lip (spec_loc_lip)</div> 1, Upper Lip (1) | 2, Lower Lip (2) | 98, Unknown (98) NA NA NA [tum_loc_head]=6 NA NA NA NA
tum_loc_lid lesion_information dropdown <div style=“margin-left: 60px;”>Source Location - Eyelid (tum_loc_lid)</div> 1, Upper Lid (1) | 2, Lower Lid (2) | 98, Unknown (98) autocomplete NA NA NA [tum_loc_head] = 3 NA NA NA NA
tum_loc_head_oth lesion_information text <div style=“margin-left: 60px;”>Lesion Location - Head/Neck - Other (tum_loc_head_oth)</div> NA NA NA [tum_loc_head_oth]=99 NA NA NA NA
tum_loc_ue lesion_information dropdown <div style=“margin-left: 40px;”>Lesion Location - Upper Extremity (tum_loc_ue)</div> 1, Shoulder (1) | 2, Upper Arm (2) | 3, Forearm (3) | 4, Hand and Fingers (4) | 5, Wrist (5) | 6, Elbow (6) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc_skin]=5 NA NA NA NA
tum_loc_le lesion_information dropdown <div style=“margin-left: 40px;”>Lesion Location - Lower Extremity (tum_loc_le)</div> 1, Upper leg (Anterior and Posterior Thigh) (1) | 2, Knee (2) | 3, Lower leg (shin and calf) (3) | 4, Foot and Toes (4) | 5, Ankle (5) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc_skin]=8 NA NA NA NA
tum_loc_skin_oth lesion_information text <div style=“margin-left: 40px;”>Lesion Location - Skin/Subcutaneous - Other (tum_loc_skin_oth)</div> NA NA NA [tum_loc_skin]=99 NA NA NA NA
tum_loc_viscera lesion_information dropdown <div style=“margin-left: 20px;”>Location of the Visceral Lesion (tum_loc_viscera)</div> 1, Adrenal (1) | 2, Bladder (2) | 3, Gallbladder (3) | 4, Kidney (4) | 5, Large Intestine (5) | 6, Liver (6) | 7, Lungs (7) | 8, Ovary (8) | 9, Pancreas (9) | 10, Small Intestine (10) | 11, Spleen (11) | 12, Stomach (12) | 13, Testis (13) | 14, Heart (14) | 98, Unknown/Not Reported (98) | 99, Other (99) Viscera broadly is meant to include organs of the chest and abdomen, but also reproductive organs autocomplete NA NA NA [tum_loc]=2 NA NA NA NA
tum_loc_viscera_other lesion_information text <div style=“margin-left: 40px;”>Location of the Visceral Lesion - other (tum_loc_viscera_other)</div> NA NA NA [tum_loc_viscera]=99 y NA NA NA NA
tum_loc_lymph lesion_information dropdown <div style=“margin-left: 20px;”>Location of the Lymphatic Lesion (tum_loc_lymph)</div> 0, Head/Neck Lymph Node, Right (0) | 1, Head/Neck Lymph Node, Left (1) | 2, Supraclavicular Lymph Node, Right (2) | 3, Supraclavicular Lymph Node, Left (3) | 4, Axillary Lymph Node, Right (4) | 5, Axillary Lymph Node, Left (5) | 6, Epitrochlear Lymph Node, Right (6) | 7, Epitrochlear Lymph Node, Left (7) | 8, Pelvic Lymph Node, Right (Deep pelvic, not inguinal) (8) | 9, Pelvic Lymph Node, Left (Deep pelvic, not inguinal) (9) | 10, Inguinal Lymph Node, Right (10) | 11, Inguinal Lymph Node, Left (11) | 12, Popliteal Fossa Lymph Node, Right (12) | 13, Popliteal Fossa Lymph Node, Left (13) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc]=3 y NA NA NA NA
tum_loc_lymph_other lesion_information text <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Location of the Lymphatic Lesion - Other <br />(tum_loc_lymph_other)</p></div> NA NA NA [tum_loc_lymph] = “99” NA NA NA NA
tum_lymph_num lesion_information dropdown <div style=“margin-left: 20px;”>How many Lymphatic Structures do you need to enter? (tum_lymph_num)</div> 1, 1 | 2, 2 | 3, 3 | 4, 4 | 5, 5 |6, 6 |7, 7 |8, 8 |9, 9 | 10, 10 autocomplete NA NA NA [tum_loc] = 3 NA NA NA NA
tum_lymph_laterality_1 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #1 (tum_lymph_laterality_1)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 1 NA NA NA NA
tum_lymph_1 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #1<br />(tum_lymph_1)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 1 NA NA NA NA
tum_loc_lymph_oth_1 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_1)</div> NA NA NA [tum_lymph_1] = “other” NA NA NA NA
tum_lymph_laterality_2 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #2 (tum_lymph_laterality_2)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 2 NA NA NA NA
tum_lymph_2 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #2<br />(tum_lymph_2)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 2 NA NA NA NA
tum_loc_lymph_oth_2 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_2)</div> NA NA NA [tum_lymph_2] = “other” NA NA NA NA
tum_lymph_laterality_3 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #3 (tum_lymph_laterality_3)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 3 NA NA NA NA
tum_lymph_3 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #3<br />(tum_lymph_3)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 3 NA NA NA NA
tum_loc_lymph_oth_3 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_3)</div> NA NA NA [tum_lymph_3] = “other” NA NA NA NA
tum_lymph_laterality_4 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #4 (tum_lymph_laterality_4)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 4 NA NA NA NA
tum_lymph_4 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #4<br />(tum_lymph_4)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 4 NA NA NA NA
tum_loc_lymph_oth_4 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_4)</div> NA NA NA [tum_lymph_4] = “other” NA NA NA NA
tum_lymph_laterality_5 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #5 (tum_lymph_laterality_5)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 5 NA NA NA NA
tum_lymph_5 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #5<br />(tum_lymph_5)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 5 NA NA NA NA
tum_loc_lymph_oth_5 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_5)</div> NA NA NA [tum_lymph_5] = “other” NA NA NA NA
tum_lymph_laterality_6 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #6 (tum_lymph_laterality_6)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 6 NA NA NA NA
tum_lymph_6 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #6<br />(tum_lymph_6)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 6 NA NA NA NA
tum_loc_lymph_oth_6 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_6)</div> NA NA NA [tum_lymph_6] = “other” NA NA NA NA
tum_lymph_laterality_7 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #7 (tum_lymph_laterality_7)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 7 NA NA NA NA
tum_lymph_7 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #7<br />(tum_lymph_7)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 7 NA NA NA NA
tum_loc_lymph_oth_7 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_7)</div> NA NA NA [tum_lymph_7] = “other” NA NA NA NA
tum_lymph_laterality_8 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #8 (tum_lymph_laterality_8)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 8 NA NA NA NA
tum_lymph_8 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #8<br />(tum_lymph_8)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 8 NA NA NA NA
tum_loc_lymph_oth_8 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_8)</div> NA NA NA [tum_lymph_8] = “other” NA NA NA NA
tum_lymph_laterality_9 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #9 (tum_lymph_laterality_9)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 9 NA NA NA NA
tum_lymph_9 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #9<br />(tum_lymph_9)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 9 NA NA NA NA
tum_loc_lymph_oth_9 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_9)</div> NA NA NA [tum_lymph_9] = “other” NA NA NA NA
tum_lymph_10 lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Involved Lymphatic Organ #10<br />(tum_lymph_10)</p></div> waldeyer_ring, waldeyer ring | tonsils, tonsils | adenoids, adenoids | nasopharynx, nasopharynx (adenoids) | lingual_tonsils_, lingual tonsils | cervical, cervical (NOS) | occipital, occipital (cervical) | submental, submental (cervical) (level IA) | preauricular, preauricular (cervical) | submandibular, submandibular (cervical) (level IB) | level_II_cervical, internal jugular (deep cervical) chain from the base of the skull to the inferior border of the hyoid bone (level II) | level_III_cervical, internal jugular (deep cervical) chain from the hyoid bone to the inferior border of the cricoid arch (level III) | level_IV_cervical, internal jugular (deep cervical) chain between the inferior border of the cricoid arch and the supraclavicular fossa (level IV) | infraclavicular, infraclavicular | level_V_cervical, posterior triangle or spinal accessory nodes (level V) | level_VI_cervical, central compartment nodes from the hyoid bone to the suprasternal notch (level VI) | level_VII_cervical, nodes inferior to the suprasternal notch in the upper mediastinum (level VII) | parotid, parotid lymph node | supraclavicular, supraclavicular (scalene) | axillary, axillary | pectoral, pectoral | peritracheal, peritracheal (mediastinal) | thymic, thymic (mediastinal) | hilar, hilar | epitrochlear, epitrochlear | brachial, brachial | splenic_hilar, splenic hilar | celiac, celiac | porta_hepatis, porta hepatis | iliac, iliac | paraaortic, paraaortic | retroperitoneal, retroperitoneal | mesenteric, mesenteric | abdominal, abdominal | inguinal, inguinal | femoral, femoral | popliteal, popliteal | spleen, spleen | other, other autocomplete NA NA NA [tum_lymph_num] >= 10 NA NA NA NA
tum_lymph_laterality_10 lesion_information dropdown <div style=“margin-left: 30px;”>Lesion Location - Laterality of Lymph Lesion #10 (tum_lymph_laterality_10)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_lymph_num] >= 10 NA NA NA NA
tum_loc_lymph_oth_10 lesion_information text <div style=“margin-left: 30px;”>Location of the Lymphatic Lesion - Other (tum_loc_lymph_oth_10)</div> NA NA NA [tum_lymph_10] = “other” NA NA NA NA
tum_loc_cns lesion_information dropdown <div style=“margin-left: 20px;”>Location of the CNS Lesion (tum_loc_cns)</div> 1, Brain (1) | 2, Leptomeningeal (2) | 3, Spinal Cord (3) | 4, Cerebrospinal Fluid (4) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc]=4 y NA NA NA NA
tum_loc_cns_other lesion_information text <div style=“margin-left: 40px;”>Location of the CNS Lesion - Other (tum_loc_cns_other)</div> NA NA NA [tum_loc_cns]=99 NA NA NA NA
tum_bone_num lesion_information dropdown <div style=“margin-left: 20px;”>How many bones do you need to enter? (tum_bone_num)</div> 1, 1 | 2, 2 | 3, 3 | 4, 4 | 5, 5 | 6, 6 | 7, 7 | 8, 8 | 9, 9 | 10, 10 autocomplete NA NA NA [tum_loc]=5 NA NA NA NA
tum_bone_laterality_1 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_1)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 1 NA NA NA NA
tum_location_bone_1 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_1)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_middle_phalange_5, hand middle phalange 5 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_middle_phalange_5, foot middle phalange 5 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 1 NA NA NA NA
tum_location_bone_other_1 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other)</div> NA NA NA [tum_location_bone_other_1] = “other” NA NA NA NA
tum_bone_laterality_2 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_2)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 2 NA NA NA NA
tum_location_bone_2 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_2)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 2 NA NA NA NA
tum_location_bone_other_2 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_2)</div> NA NA NA [tum_location_bone_other_2] = “other” NA NA NA NA
tum_bone_laterality_3 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_3)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 3 NA NA NA NA
tum_location_bone_3 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_3)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 3 NA NA NA NA
tum_location_bone_other_3 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_3)</div> NA NA NA [tum_location_bone_other_3] = “other” NA NA NA NA
tum_bone_laterality_4 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_4)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 4 NA NA NA NA
tum_location_bone_4 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_4)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 4 NA NA NA NA
tum_location_bone_other_4 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_4)</div> NA NA NA [tum_location_bone_other_4] = “other” NA NA NA NA
tum_bone_laterality_5 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_5)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 5 NA NA NA NA
tum_location_bone_5 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_5)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 5 NA NA NA NA
tum_location_bone_other_5 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_5)</div> NA NA NA [tum_location_bone_other_5] = “other” NA NA NA NA
tum_bone_laterality_6 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_6)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 6 NA NA NA NA
tum_location_bone_6 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_6)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 6 NA NA NA NA
tum_location_bone_other_6 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_6)</div> NA NA NA [tum_location_bone_other_6] = “other” NA NA NA NA
tum_bone_laterality_7 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_7)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 7 NA NA NA NA
tum_location_bone_7 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_7)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 7 NA NA NA NA
tum_location_bone_other_7 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_7)</div> NA NA NA [tum_location_bone_other_7] = “other” NA NA NA NA
tum_bone_laterality_8 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_8)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 8 NA NA NA NA
tum_location_bone_8 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_8)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 8 NA NA NA NA
tum_location_bone_other_8 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_8)</div> NA NA NA [tum_location_bone_other_8] = “other” NA NA NA NA
tum_bone_laterality_9 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_9)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 9 NA NA NA NA
tum_location_bone_9 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_9)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 9 NA NA NA NA
tum_location_bone_other_9 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_9)</div> NA NA NA [tum_location_bone_other_9] = “other” NA NA NA NA
tum_bone_laterality_10 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone Laterality (tum_bone_laterality_10)</div> right, Right | left, Left | midline, Midline | na, Not Applicable autocomplete NA NA NA [tum_bone_num] >= 10 NA NA NA NA
tum_location_bone_10 lesion_information dropdown <div style=“margin-left: 20px;”>Lesion Location - Bone (tum_location_bone_10)</div> frontal_bones, frontal bones | parietal_bone, parietal bone | temporal_bones, temporal bones | occipital_bone, occipital bone | sphenoid_bone, sphenoid bone | ethmoid_bone, ethmoid bone | mandible, mandible | maxilla, maxilla | palatine_bone, palatine bone | zygomatic_bone, zygomatic bone | nasal_bone, nasal bone | lacrimal_bone, lacrimal bone | vomer_bone, vomer bone | inferior_nasal_conae, inferior nasal conchae | malleus, malleus | incus, incus | stapes, stapes | hyoid_bone, hyoid bone | scapula_or_shoulder_badde, scapula or shoulder blade | clavicle_or_collarbone, clavicle or collarbone | sternum, sternum | rib_1, rib 1 | rib_2, rib 2 | rib_3, rib 3 | rib_4, rib 4 | rib_5, rib 5 | rib_6, rib 6 | rib_7, rib 7 | rib_8, rib 8 | rib_9, rib 9 | rib_10, rib 10 | rib_11, rib 11 | rib_12, rib 12 | cervical_vertebrae_1, cervical vertebrae 1 | cervical_vertebrae_2, cervical vertebrae 2 | cervical_vertebrae_3, cervical vertebrae 3 | cervical_vertebrae_4, cervical vertebrae 4 | cervical_vertebrae_5, cervical vertebrae 5 | cervical_vertebrae_6, cervical vertebrae 6 | cervical_vertebrae_7, cervical vertebrae 7 | thoracic_vertebrae_1, thoracic vertebrae 1 | thoracic_vertebrae_2, thoracic vertebrae 2 | thoracic_vertebrae_3, thoracic vertebrae 3 | thoracic_vertebrae_4, thoracic vertebrae 4 | thoracic_vertebrae_5, thoracic vertebrae 5 | thoracic_vertebrae_6, thoracic vertebrae 6 | thoracic_vertebrae_7, thoracic vertebrae 7 | thoracic_vertebrae_8, thoracic vertebrae 8 | thoracic_vertebrae_9, thoracic vertebrae 9 | thoracic_vertebrae_10, thoracic vertebrae 10 | thoracic_vertebrae_11, thoracic vertebrae 11 | thoracic_vertebrae_12, thoracic vertebrae 12 | lumbar_vertebrae_1, lumbar vertebrae 1 | lumbar_vertebrae_2, lumbar vertebrae 2 | lumbar_vertebrae_3, lumbar vertebrae 3 | lumbar_vertebrae_4, lumbar vertebrae 4 | lumbar_vertebrae_5, lumbar vertebrae 5 | humerus, humerus | radius, radius | ulna, ulna | scaphoid_bone, scaphoid bone | lunate_bone, lunate bone | triquetral_bone, triquetral bone | pisiform_bone, pisiform bone | trapezium, trapezium | trapezoid_bone, trapezoid bone | capitate_bone, capitate bone | hamate_bone, hamate bone | metacarpal_bone_1, metacarpal bone 1 | metacarpal_bone_2, metacarpal bone 2 | metacarpal_bone_3, metacarpal bone 3 | metacarpal_bone_4, metacarpal bone 4 | metacarpal_bone_5, metacarpal bone 5 | hand_proximal_phalange_1, hand proximal phalange 1 | hand_proximal_phalange_2, hand proximal phalange 2 | hand_proximal_phalange_3, hand proximal phalange 3 | hand_proximal_phalange_4, hand proximal phalange 4 | hand_proximal_phalange_5, hand proximal phalange 5 | hand_middle_phalange_1, hand middle phalange 1 | hand_middle_phalange_2, hand middle phalange 2 | hand_middle_phalange_3, hand middle phalange 3 | hand_middle_phalange_4, hand middle phalange 4 | hand_distal_phalange_1, hand distal phalange 1 | hand_distal_phalange_2, hand distal phalange 2 | hand_distal_phalange_3, hand distal phalange 3 | hand_distal_phalange_4, hand distal phalange 4 | hand_distal_phalange_5, hand distal phalange 5 | coccyx, coccyx | sacrum, sacrum | ilium, ilium | ishium, ishium | pubis, pubis | ossa_coxae, ossa coxae (hip bones or innominate bones) | femur, femur | patella, patella | tibia, tibia | fibula, fibula | calcaneus, calcaneus (heel bone) | talus, talus | navicular_bone, navicular bone | medial_cuneiform_bone, medial cuneiform bone | intermediate_cuneiform_bone, intermediate cuneiform bone | lateral_cuneiform_bone, lateral cuneiform bone | cuboid_bone, cuboid bone | metatarsal_bone_1, metatarsal bone 1 | metatarsal_bone_2, metatarsal bone 2 | metatarsal_bone_3, metatarsal bone 3 | metatarsal_bone_4, metatarsal bone 4 | metatarsal_bone_5, metatarsal bone 5 | foot_proximal_phalange_1, foot proximal phalange 1 | foot_proximal_phalange_2, foot proximal phalange 2 | foot_proximal_phalange_3, foot proximal phalange 3 | foot_proximal_phalange_4, foot proximal phalange 4 | foot_proximal_phalange_5, foot proximal phalange 5 | foot_middle_phalange_1, foot middle phalange 1 | foot_middle_phalange_2, foot middle phalange 2 | foot_middle_phalange_3, foot middle phalange 3 | foot_middle_phalange_4, foot middle phalange 4 | foot_distal_phalange_1, foot distal phalange 1 | foot_distal_phalange_2, foot distal phalange 2 | foot_distal_phalange_3, foot distal phalange 3 | foot_distal_phalange_4, foot distal phalange 4 | foot_distal_phalange_5, foot distal phalange 5 | other, other autocomplete NA NA NA [tum_bone_num] >= 10 NA NA NA NA
tum_location_bone_other_10 lesion_information text <div style=“margin-left: 40px;”>Location of the Bone Lesion - Other (tum_location_bone_other_10)</div> NA NA NA [tum_location_bone_other_10] = “other” NA NA NA NA
eye_rl lesion_information dropdown <div style=“margin-left: 20px;”>Right Eye vs. Left Eye (eye_rl)</div> 1, Right Eye (1) | 2, Left Eye (2) | 98, Unknown/Not Reported (98) autocomplete NA NA NA [tum_loc]=6 y NA NA NA NA
tum_loc_muc lesion_information dropdown <div style=“margin-left: 20px;”>Location of the Mucosal Lesion (tum_loc_muc)</div> 1, Nasal Mucosa (1) | 2, Oral Mucosa (including tongue) (2) | 3, Esophagus (3) | 4, Cervix (4) | 5, Vagina (5) | 6, Anus (6) | 98, Unknown/Not Reported (98) | 99, Other (99) autocomplete NA NA NA [tum_loc]=7 NA NA NA NA
tum_loc_muc_other lesion_information text <div style=“margin-left: 40px;”>Location of the Mucosal Lesion - Other (tum_loc_muc_other)</div> NA NA NA [tum_loc_muc]=99 NA NA NA NA
tum_loc_other lesion_information text <div style=“margin-left: 20px;”>Lesion Location - Other (tum_loc_other)</div> NA NA NA [tum_loc]=99 NA NA NA NA
les_pex_hdr lesion_information descriptive <div style=“background-color:lightyellow”>Physical Exam at Presentation</div> NA NA NA [tum_num] <> 2 AND [tum_num] <> 98 NA NA NA NA
les_size_rad_hdr lesion_information descriptive <div style=“padding-left: 5px; border-left: 5px solid red; background-color:wheat;”>Radiographic size data for this lesion should be entered in the imaging instrument</div> NA NA NA [tum_num] <> 2 AND [tum_num] <> 98 NA NA NA NA
tum_size_clin_yn lesion_information dropdown Was Lesion [current-instance] Size assessed by physical exam at time of presentation? (tum_size_clin_yn) 0, No (0) | 1, Yes (1) autocomplete NA NA NA [tum_num] <> 2 AND [tum_num] <> 98 NA NA NA NA
clin_dim_1_date lesion_information text <p style=“margin-left: 20px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date)</p> date_mdy NA NA NA [tum_size_clin_yn] = 1 NA NA NA NA
tum_dim_clin lesion_information dropdown <div style=“margin-left: 20px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [tum_size_clin_yn]=1 NA NA NA NA
clin_dim_1_1 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_1)</div> number 0 50 NA [tum_dim_clin]=1 OR [tum_dim_clin]=2 or [tum_dim_clin]=3 NA NA NA NA
clin_dim_1_2 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_1_2)</div> number 0 50 NA [tum_dim_clin]=2 or [tum_dim_clin]=3 NA NA NA NA
clin_dim_1_3 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_1_3)</div> number 0 50 NA [tum_dim_clin]=3 NA NA NA NA
tum_dim_clin_unit lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin]=1 OR [tum_dim_clin]=2 or [tum_dim_clin]=3 NA NA NA NA
les_pex_hdr_fu lesion_information descriptive <div style=“background-color:lightyellow”>Follow Up Physical Examinations</div> NA NA NA [tum_num] <> 2 AND [tum_num] <> 98 NA NA NA NA
fu_measurments_num lesion_information dropdown <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>How many follow up visits do you need to enter?(fu_measurments_num)</p></div> 0, 0 | 1, 1 | 2, 2 | 3, 3 | 4, 4 | 5, 5 autocomplete NA NA NA NA NA NA NA
clin_dim_1_date_fu_1 lesion_information text <p style=“margin-left: 30px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date_fu_1)</p> date_mdy NA NA NA [fu_measurments_num] >= 1 NA NA NA NA
tum_dim_clin_fu_1 lesion_information dropdown <div style=“margin-left: 30px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin_fu_1)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [fu_measurments_num] >=1 NA NA NA NA
clin_dim_1_fu_1 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_fu_1)</div> number 0 50 NA [tum_dim_clin_fu_1]=1 OR [tum_dim_clin_fu_1]=2 or [tum_dim_clin_fu_1]=3 NA NA NA NA
clin_dim_2_fu_1 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_2_fu_1)</div> number 0 50 NA [tum_dim_clin_fu_1]=2 or [tum_dim_clin_fu_1]=3 NA NA NA NA
clin_dim_3_fu_1 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_3_fu_1)</div> number 0 50 NA [tum_dim_clin_fu_1]=3 NA NA NA NA
tum_dim_clin_unit_fu_1 lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit_fu_1)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin_fu_1]=1 OR [tum_dim_clin_fu_1]=2 or [tum_dim_clin_fu_1]=3 NA NA NA NA
clin_dim_1_date_fu_2 lesion_information text <p style=“margin-left: 30px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date_fu_2)</p> date_mdy NA NA NA [fu_measurments_num] >= 2 NA NA NA NA
tum_dim_clin_fu_2 lesion_information dropdown <div style=“margin-left: 30px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin_fu_2)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [fu_measurments_num] >=2 NA NA NA NA
clin_dim_1_fu_2 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_fu_2)</div> number 0 50 NA [tum_dim_clin_fu_2]=1 OR [tum_dim_clin_fu_2]=2 or [tum_dim_clin_fu_2]=3 NA NA NA NA
clin_dim_2_fu_2 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_2_fu_2)</div> number 0 50 NA [tum_dim_clin_fu_2]=2 or [tum_dim_clin_fu_2]=3 NA NA NA NA
clin_dim_3_fu_2 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_3_fu_2)</div> number 0 50 NA [tum_dim_clin_fu_2]=3 NA NA NA NA
tum_dim_clin_unit_fu_2 lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit_fu_2)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin_fu_2]=1 OR [tum_dim_clin_fu_2]=2 or [tum_dim_clin_fu_2]=3 NA NA NA NA
clin_dim_1_date_fu_3 lesion_information text <p style=“margin-left: 30px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date_fu_3)</p> date_mdy NA NA NA [fu_measurments_num] >= 3 NA NA NA NA
tum_dim_clin_fu_3 lesion_information dropdown <div style=“margin-left: 30px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin_fu_3)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [fu_measurments_num] >=3 NA NA NA NA
clin_dim_1_fu_3 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_fu_3)</div> number 0 50 NA [tum_dim_clin_fu_3]=1 OR [tum_dim_clin_fu_3]=2 or [tum_dim_clin_fu_3]=3 NA NA NA NA
clin_dim_2_fu_3 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_2_fu_3)</div> number 0 50 NA [tum_dim_clin_fu_3]=2 or [tum_dim_clin_fu_3]=3 NA NA NA NA
clin_dim_3_fu_3 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_3_fu_3)</div> number 0 50 NA [tum_dim_clin_fu_3]=3 NA NA NA NA
tum_dim_clin_unit_fu_3 lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit_fu_3)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin_fu_3]=1 OR [tum_dim_clin_fu_3]=2 or [tum_dim_clin_fu_3]=3 NA NA NA NA
clin_dim_1_date_fu_4 lesion_information text <p style=“margin-left: 30px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date_fu_4)</p> date_mdy NA NA NA [fu_measurments_num] >= 4 NA NA NA NA
tum_dim_clin_fu_4 lesion_information dropdown <div style=“margin-left: 30px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin_fu_4)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [fu_measurments_num] >=4 NA NA NA NA
clin_dim_1_fu_4 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_fu_4)</div> number 0 50 NA [tum_dim_clin_fu_4]=1 OR [tum_dim_clin_fu_4]=2 or [tum_dim_clin_fu_4]=3 NA NA NA NA
clin_dim_2_fu_4 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_2_fu_4)</div> number 0 50 NA [tum_dim_clin_fu_4]=2 or [tum_dim_clin_fu_4]=3 NA NA NA NA
clin_dim_3_fu_4 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_3_fu_4)</div> number 0 50 NA [tum_dim_clin_fu_4]=3 NA NA NA NA
tum_dim_clin_unit_fu_4 lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit_fu_4)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin_fu_4]=1 OR [tum_dim_clin_fu_4]=2 or [tum_dim_clin_fu_4]=3 NA NA NA NA
clin_dim_1_date_fu_5 lesion_information text <p style=“margin-left: 30px;”>Date of Physical Exam Measurement<br />(clin_dim_1_date_fu_5)</p> date_mdy NA NA NA [fu_measurments_num] >= 5 NA NA NA NA
tum_dim_clin_fu_5 lesion_information dropdown <div style=“margin-left: 30px;”>Number of tumor dimensions assessed by physical exam (tum_dim_clin_fu_5)</div> 1, 1 (1) | 2, 2 (2) | 3, 3 (3) autocomplete NA NA NA [fu_measurments_num] >=5 NA NA NA NA
clin_dim_1_fu_5 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #1 (clin_dim_1_fu_5)</div> number 0 50 NA [tum_dim_clin_fu_5]=1 OR [tum_dim_clin_fu_5]=2 or [tum_dim_clin_fu_5]=3 NA NA NA NA
clin_dim_2_fu_5 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #2 (clin_dim_2_fu_5)</div> number 0 50 NA [tum_dim_clin_fu_5]=2 or [tum_dim_clin_fu_5]=3 NA NA NA NA
clin_dim_3_fu_5 lesion_information text <div style=“margin-left: 40px;”>Physical Exam Measurement Dimension #3 (clin_dim_3_fu_5)</div> number 0 50 NA [tum_dim_clin_fu_5]=3 NA NA NA NA
tum_dim_clin_unit_fu_5 lesion_information dropdown <p style=“margin-left: 40px;”>Tumor Dimensions assessed by Physical Exam - Units<br/>(tum_dim_clin_unit_fu_5)</p> 0, mm (0) | 1, cm (1) autocomplete NA NA NA [tum_dim_clin_fu_5]=1 OR [tum_dim_clin_fu_5]=2 or [tum_dim_clin_fu_5]=3 NA NA NA NA
tum_ned_yn lesion_information Response to Treatment dropdown <div class=“rich-text-field-label”><p>Was this lesion removed or had a complete response to therapy (i.e. the lesion is now NED)?<br />(tum_ned_yn)</p></div> 0, No (0) | 1, Yes (1) | 98, Unknown/Not Reported (98) For lymph nodes, “NED” refers to size <1 cm in short axis autocomplete NA NA NA NA NA NA NA
surg_date_pipe_hdr_1 lesion_information descriptive <div style=“margin-left: 0px; padding-left: 5px; border-left: 5px solid red; background-color:wheat;”>For Reference: Dates of Surgery and Pathology Instrument</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_surg][1] <> "" NA NA NA NA
surg_date_piped_1 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Surgery #1: [lesion_tag_surg][1], [surg_dtc_1][1]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_surg][1] <> "" NA NA NA NA
surg_date_piped_2 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Surgery #2: [lesion_tag_surg][2], [surg_dtc_1][2]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_surg][2] <> "" NA NA NA NA
surg_date_piped_3 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Surgery #3: [lesion_tag_surg][3], [surg_dtc_1][3]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_surg][3] <> "" NA NA NA NA
path_date_piped_1 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Path Report #1: [lesion_tag_path][1], [path_coll_date][1]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_path][1] <> "" NA NA NA NA
path_date_piped_2 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Path Report #1: [lesion_tag_path][2], [path_coll_date][2]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_path][2] <> "" NA NA NA NA
path_date_piped_3 lesion_information descriptive <div style=“background-color:lavender; margin-left: 0px”>Path Report #3: [lesion_tag_path][3], [path_coll_date][3]</div> NA NA NA [tum_ned_yn] = 1 AND [lesion_tag_path][3] <> "" NA NA NA NA
tum_ned_dtc lesion_information text <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Date lesion was first NED<br />(tum_ned_dtc)</p></div> Lesions that underwent curative surgery, the date of surgery would be the date entered here. For lesions that are cured from XRT or systemic therapy, this date corresponds to the first date the lesion was appreciated to be NED. That may be a radiologic or clinical examination. date_mdy NA NA NA [tum_ned_yn] = 1 NA NA NA NA
tum_ned_dtc_approx lesion_information checkbox <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Was the date the lesion was rendered NED an an approximation?<br />(tum_ned_dtc_approx)</p></div> 1, Click if the above date was an approximation In some circumstances the precise date of detection is not known, if that is the case, check this box and put in the first of the month NA NA NA NA NA NA NA
les_pic_hdr lesion_information descriptive <div style=“background-color:lightyellow”>Clinical Photography</div> NA NA NA NA NA NA NA
tum_image_yn lesion_information dropdown Is a Clinical Photograph of Lesion [current-instance] available to review and upload? (tum_image_yn) 0, No (0) | 1, Yes (1) autocomplete NA NA NA NA NA NA NA
tum_image_dtc lesion_information text <div style=“margin-left: 20px;”>Date of Clinical Photograph (tum_image_dtc)</div> date_mdy NA NA NA [tum_image_yn] = ‘1’ NA NA NA NA
tum_image lesion_information file <div style=“margin-left: 20px;”>Clinical Photograph of Lesion (tum_image)</div> Images should be uploaded with filenames under the following format: (patient number)(lesion number)(date of detection).jpg/png. For example, for patient 80, lesion 2, detected on 1/5/2020: 80_2_1_5_2020.jpg. NA NA NA [tum_image_yn] = ‘1’ NA NA NA NA
les_notes_hdr lesion_information descriptive <div style=“background-color: lightyellow;”>Additional Notes</div> NA NA NA NA NA NA NA
les_notes lesion_information notes <div class=“rich-text-field-label”><p>Additional Notes - Free Text<br />(les_notes)</p></div> NA NA NA NA NA NA NA
les_qc_hdr lesion_information descriptive <div class=“rich-text-field-label”><div style=“margin-left: 0px; background-color: lightyellow;”>Quality Control</div></div> NA NA NA NA NA NA NA
les_qcdash lesion_information checkbox <div style=“margin-left: 0px;”> <b>Lesion Information, Instance [current-instance]</b> Quality Control Dashboard</div> daf, Legacy Data Abstractor Flag (daf) | dac, First Pass Complete (dac) | dmf, Legacy Data Manager Flag (dmf) | dmqc, Second Pass Complete (dmqc) | tpc, Third Pass Complete (tpc) | lpf, Legacy Longitudinal Provider Flag (lpf) | lpqc, Longitudinal Provider Quality Check (lpqc) | pds1, PDS Release 1 Sign-off (v4, circa 2/1/21) (pds1) NA NA NA NA NA NA NA
les_daf_note lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Data Abstractor Flag Note</p></div> NA NA NA [les_qcdash(daf)] = 1 NA NA NA NA
les_dmf_note lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Data Manager Flag Note</p></div> NA NA NA [les_qcdash(dmf)] = 1 NA NA NA NA
les_lpf_note lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 30px;”>Longitudinal Provider Flag Note</p></div> NA NA NA [les_qcdash(lpf)] = 1 NA NA NA NA
les_flag_yn_1 lesion_information radio Add Flag #1? 1, 1. Yes (1) NA NA NA NA NA NA NA
les_details_flag_1 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Flag #1 - Details</p></div> NA NA NA [les_flag_yn_1] = 1 NA NA NA NA
les_resolved_flag_1 lesion_information radio <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #1 - Resolved?</p></div> 1, Resolved (1) NA NA NA [les_flag_yn_1] = 1 NA NA NA NA
les_resp_flag_1 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #1 - Response</p></div> NA NA NA [les_resolved_flag_1] = 1 NA NA NA NA
les_flag_yn_2 lesion_information radio Add Flag #2? 1, 1. Yes (1) NA NA NA [les_flag_yn_1] = 1 NA NA NA NA
les_details_flag_2 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Flag #2 - Details</p></div> NA NA NA [les_flag_yn_2] = 1 NA NA NA NA
les_resolved_flag_2 lesion_information radio <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #2 - Resolved?</p></div> 1, Resolved (1) NA NA NA [les_flag_yn_2] = 1 NA NA NA NA
les_resp_flag_2 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #2 - Response</p></div> NA NA NA [les_resolved_flag_2] = 1 NA NA NA NA
les_flag_yn_3 lesion_information radio Add Flag #3? 1, 1. Yes (1) NA NA NA [les_flag_yn_2] = 1 NA NA NA NA
les_details_flag_3 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 40px;”>Flag #3 - Details</p></div> NA NA NA [les_flag_yn_3] = 1 NA NA NA NA
les_resolved_flag_3 lesion_information radio <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #3 - Resolved?</p></div> 1, Resolved (1) NA NA NA [les_flag_yn_3] = 1 NA NA NA NA
les_resp_flag_3 lesion_information notes <div class=“rich-text-field-label”><p style=“padding-left: 80px;”>Flag #3 - Response</p></div> NA NA NA [les_resolved_flag_3] = 1 NA NA NA NA
les_unresolved_flag lesion_information calc Flags Unresolved? HIDDEN FIELD if yes, variable = 1 If no, variable = "" if((([les_flag_yn_1] = 1 AND [les_resolved_flag_1] != 1) OR ([les_flag_yn_2] = 1 AND [les_resolved_flag_2] != 1) OR ([les_flag_yn_3] = 1 AND [les_resolved_flag_3] != 1)), 1, "") NA NA NA NA NA NA NA HIDDEN?
les_ftr lesion_information descriptive <div style=“margin-left: 0px; background-color:#D2DFF0; font-weight:lighter;”>Editing <b>“Lesion Information, Instance [current-instance]”</b> for Record ID <b>[record_id]</b>  DOB: [brth_dtc]</div> NA NA NA NA NA NA NA

Results

Comprehensive and Streamlined Capture of Clinical Tumor Characteristics

Given the complexities of clinical oncology, nuanced collection of a wide variety of clinical tumor characteristics is important in order to advance our current understanding of tumor biology. Therefore, the LII provides a structured format to collect over 150 data elements. The LII is a repeating instrument, therefore a limitless number of cancer lesions can be captured using the LII. Each subsequent lesion is marked by a unique instrument instance, which allows distinct lesions to be differentiated on the back end in a statistical package.

To balance the tension between detailed and comprehensive capture of clinical tumor characteristics on the one hand, and feasibility of real-world data abstraction on the other, the LII is partitioned into the following sections: 1) Lesion Detection Data, 2) Clinical Description of the Lesion, 3) Physical Examination at Presentation, 4) Follow Up Physical Examinations, 5) Response to Treatment Data and 5) Clinical Photography. In order to streamline the UI and enhance the UX of the LII, branching logic was used to limit the initial data collection instruments to 13 fields (Figure 1). A more detailed overview of the elements in these partitions if provided in the subsequent sections.

Figure 1: Lesion Information Instrument

Figure 1: Lesion Information Instrument. Depicted above is the user interface of the LII when first accessed by an investigator. It is organized in five sections. The majority of the greater than 150 fields are hidden from view until they activated by the appropriate branching logic.



The Lesion Tag, a key metadata variable

A hallmark of structured data collection is the creation of fields with a defined range of data elements. This allows for a restricted selection of information per field to ensure a standardized and unified capture of data. This is often accomplished with the incorporation of drop-down menus, check boxes or free text with specified value ranges. However, there are situations when unrestricted free text has utility in patient-level data collection. We incorporated a free text field labeled “Lesion Tag” that takes a unique character string to characterize the particular lesion being captured, e.g. “Right Arm Primary Lesion”. This unique character string has several purposes. First, it provides useful, though non-essential, metadata to help characterize the cancer lesion. Second, and perhaps more importantly, when the LII is used in conjunction with other instruments, such as the aforementioned Genomics Instrument, the variable lesion_tag acts a “key”. The same character string can be used across data collection instruments within a project and allow for “key/value” pairing to link distinct data tables in the back end. For example, the Genomics Instrument contains a variable lesion_tag_genomics. Given that both LII and the Genomics Instrument are repeating instruments, if the same string is used for lesion_tag and lesion_tag_genomics a data scientist can link tables containing clinical tumor characteristics and CGD that pertain to the same cancer lesion.

Lesion Detection

An understanding of the natural history of a malignancy is critical to gain insights into cancer biology. Reliably documenting the initial presentation of a cancer lesion, a necessity to understand its natural history, is a particular challenge in the real-world setting. To standardize the collection of this data element, the field “Date of First Documentation” specifies that the date entered is the first date of a clinical encounter at which the lesion was documented. If the exact day, month and year of that encounter is not known, a subsequent modifier, tum_dtctn_dt_aprox allows a data capture specialist (DCS) to alert that the previous date was only an approximation. In addition, data regarding histological confirmation of the diagnosis is collected in “Lesion Detection” section.

Clinical Description of Lesion

Information regarding the type of lesion (e.g. primary vs. metastasis), as well as location of the lesion are collected in the “Clinical Description of Lesion” section. In addition to capturing whether a cancer lesion is a primary tumor or metastatic lesion, the variable tum_type allows for documentation of lesions as unknown primary lesions or local recurrences. In situations where there is uncertainty about the identity of a lesion, tum_type permits entry of information documenting that a lesion is of unclear etiology/not confirmed.

Topography

Lesion location (tum_loc) is the parent variable within a hierarchy of branching logic fields designed to collect information on the anatomical location of a lesion. tum_loc is a single answer drop-down list with the following choices: 1, Skin/Muscle/Soft Tissue; 2, Viscera; 3, Lymphatic; 4, CNS/Brain; 5, Bone; 6, Ocular; 7, Mucosa; 8, Peritoneum/Retroperitoneum; 9, Bodily fluids (e.g. ascites, pleural effusions). Data capture is then guided by a series of branching logic features to further refine the location of the cancer lesion.

The Lesion Information instrument was designed to capture 651 distinct anatomical structures (Table 2).

Table 2: Anatomic Structures Catured in the LII
Anatomic Structure
Anterior Medial Left Abdomen Skin
Anterior Midline Left Abdomen Skin
Anterior Lateral Left Abdomen Skin
Left Abdominal Lymphoid Tissue
Left Adenoid Lymphoid Tissue
Left Adrenal
Anterior Medial Left Ankle Skin
Anterior Midline Left Ankle Skin
Anterior Lateral Left Ankle Skin
Posterior Lateral Left Ankle Skin
Posterior Midline Left Ankle Skin
Posterior Medial Left Ankle Skin
Left Axillary Lymphoid Tissue
Posterior Lateral Left Back Skin
Midline Left Back Skin
Posterior Medial Left Back Skin
Medial Left Back Skin
Left Bladder
Left Brachial Lymphoid Tissue
Posterior Lateral Left Buttocks Skin
Midline Left Buttocks Skin
Posterior Medial Left Buttocks Skin
Left Buttocks Skin
Medial Left Buttocks Skin
Left Calcaneus Bone
Left Capitate Bone
Left Celiac Lymphoid Tissue
Anterior Medial Left Cheek Skin
Anterior Midline Left Cheek Skin
Anterior Lateral Left Cheek Skin
Anterior Medial Left Chest Skin
Anterior Midline Left Chest Skin
Anterior Lateral Left Chest Skin
Anterior Medial Left Chin Skin
Anterior Midline Left Chin Skin
Anterior Lateral Left Chin Skin
Left Clavicle Or Collarbone Bone
Left Cuboid Bone
Anterior Medial Left Ear Skin
Anterior Lateral Left Ear Skin
Posterior Medial Left Ear Skin
Posterior Lateral Left Ear Skin
Posterior Midline Left Ear Skin
Anterior Medial Left Elbow Skin
Anterior Midline Left Elbow Skin
Anterior Lateral Left Elbow Skin
Posterior Lateral Left Elbow Skin
Posterior Midline Left Elbow Skin
Posterior Medial Left Elbow Skin
Left Epitrochlear Lymphoid Tissue
Left Ethmoid Bone
Anterior Medial Left Eyebrow Skin
Anterior Midline Left Eyebrow Skin
Anterior Lateral Left Eyebrow Skin
Anterior Medial Left Eyelid Skin
Anterior Midline Left Eyelid Skin
Anterior Lateral Left Eyelid Skin
Left Femoral Lymphoid Tissue
Left Femur Bone
Left Fibula Bone
Anterior Medial Left Foot And Toes Skin
Anterior Midline Left Foot And Toes Skin
Anterior Lateral Left Foot And Toes Skin
Posterior Lateral Left Foot And Toes Skin
Posterior Midline Left Foot And Toes Skin
Left Foot Distal Phalange 1 Bone
Left Foot Distal Phalange 2 Bone
Left Foot Distal Phalange 3 Bone
Left Foot Distal Phalange 4 Bone
Left Foot Distal Phalange 5 Bone
Left Foot Middle Phalange 2 Bone
Left Foot Middle Phalange 3 Bone
Left Foot Middle Phalange 4 Bone
Left Foot Middle Phalange 5 Bone
Left Foot Proximal Phalange 1 Bone
Left Foot Proximal Phalange 2 Bone
Left Foot Proximal Phalange 3 Bone
Left Foot Proximal Phalange 4 Bone
Left Foot Proximal Phalange 5 Bone
Anterior Medial Left Forearm Skin
Anterior Midline Left Forearm Skin
Anterior Lateral Left Forearm Skin
Posterior Lateral Left Forearm Skin
Posterior Midline Left Forearm Skin
Posterior Medial Left Forearm Skin
Anterior Medial Left Forehead Skin
Anterior Midline Left Forehead Skin
Lateral Left Forehead Skin
Anterior Lateral Left Forehead Skin
Left Frontal Bone
Left Gallbladder
Anterior Medial Left Genitalia Skin
Anterior Midline Left Genitalia Skin
Midline Left Genitalia Skin
Posterior Lateral Left Genitalia Skin
Posterior Midline Left Genitalia Skin
Posterior Medial Left Genitalia Skin
Left Hamate Bone
Anterior Medial Left Hand And Fingers Skin
Anterior Midline Left Hand And Fingers Skin
Anterior Lateral Left Hand And Fingers Skin
Posterior Lateral Left Hand And Fingers Skin
Posterior Midline Left Hand And Fingers Skin
Posterior Medial Left Hand And Fingers Skin
Left Hand Distal Phalange 1 Bone
Left Hand Distal Phalange 2 Bone
Left Hand Distal Phalange 3 Bone
Left Hand Distal Phalange 4 Bone
Left Hand Distal Phalange 5 Bone
Left Hand Middle Phalange 2 Bone
Left Hand Middle Phalange 3 Bone
Left Hand Middle Phalange 4 Bone
Left Hand Middle Phalange 5 Bone
Left Hand Proximal Phalange 1 Bone
Left Hand Proximal Phalange 2 Bone
Left Hand Proximal Phalange 3 Bone
Left Hand Proximal Phalange 4 Bone
Left Hand Proximal Phalange 5 Bone
Left Heart
Left Hilar Lymphoid Tissue
Left Humerus Bone
Left Iliac Lymphoid Tissue
Left Ilium Bone
Left Incus Bone
Left Inferior Nasal Conchae Bone
Left Infraclavicular Lymphoid Tissue
Left Inguinal Lymphoid Tissue
Left Intermediate Cuneiform Bone
Left Ischium Bone
Left Kidney
Anterior Medial Left Knee Skin
Anterior Midline Left Knee Skin
Anterior Lateral Left Knee Skin
Posterior Lateral Left Knee Skin
Posterior Midline Left Knee Skin
Posterior Medial Left Knee Skin
Left Lacrimal Bone
Left Large Intestine
Left Lateral Cuneiform Bone
Left Level Ii Cervical Lymphoid Tissue
Left Level Iii Cervical Lymphoid Tissue
Left Level Iv Cervical Lymphoid Tissue
Left Level V Cervical Lymphoid Tissue
Left Level Vi Cervical Lymphoid Tissue
Left Level Vii Cervical Lymphoid Tissue
Left Lingual Tonsils Lymphoid Tissue
Anterior Medial Left Lip Skin
Anterior Lateral Left Lip Skin
Anterior Midline Left Lip Skin
Left Liver
Anterior Medial Left Lower Leg (Shin And Calf) Skin
Anterior Midline Left Lower Leg (Shin And Calf) Skin
Anterior Lateral Left Lower Leg (Shin And Calf) Skin
Posterior Lateral Left Lower Leg (Shin And Calf) Skin
Posterior Midline Left Lower Leg (Shin And Calf) Skin
Posterior Medial Left Lower Leg (Shin And Calf) Skin
Left Lunate Bone
Left Lungs
Left Malleus Bone
Left Mandible Bone
Left Maxilla Bone
Left Medial Cuneiform Bone
Left Mesenteric Lymphoid Tissue
Left Metacarpal 1 Bone
Left Metacarpal 2 Bone
Left Metacarpal 3 Bone
Left Metacarpal 4 Bone
Left Metacarpal 5 Bone
Left Metatarsal 1 Bone
Left Metatarsal 2 Bone
Left Metatarsal 3 Bone
Left Metatarsal 4 Bone
Left Metatarsal 5 Bone
Left Nasal Bone
Left Nasopharynx Lymphoid Tissue
Left Navicular Bone
Anterior Medial Left Neck Skin
Anterior Midline Left Neck Skin
Anterior Lateral Left Neck Skin
Posterior Lateral Left Neck Skin
Posterior Midline Left Neck Skin
Posterior Medial Left Neck Skin
Anterior Medial Left Nose Skin
Anterior Midline Left Nose Skin
Anterior Lateral Left Nose Skin
Left Occipital Lymphoid Tissue
Left Occipital Bone
Left Ossa Coxae Bone
Left Ovary
Left Palatine Bone
Left Pancreas
Left Paraaortic Lymphoid Tissue
Left Parietal Bone
Left Parotid Lymphoid Tissue
Left Patella Bone
Left Pectoral Lymphoid Tissue
Left Peritracheal Lymphoid Tissue
Left Pisiform Bone
Left Popliteal Lymphoid Tissue
Left Porta Hepatis Lymphoid Tissue
Left Preauricular Lymphoid Tissue
Left Pubis Bone
Left Radius Bone
Left Retroperitoneal Lymphoid Tissue
Left Rib 1 Bone
Left Rib 10 Bone
Left Rib 11 Bone
Left Rib 12 Bone
Left Rib 2 Bone
Left Rib 3 Bone
Left Rib 4 Bone
Left Rib 5 Bone
Left Rib 6 Bone
Left Rib 7 Bone
Left Rib 8 Bone
Left Rib 9 Bone
Anterior Medial Left Scalp Skin
Anterior Midline Left Scalp Skin
Anterior Lateral Left Scalp Skin
Posterior Lateral Left Scalp Skin
Posterior Medial Left Scalp Skin
Posterior Midline Left Scalp Skin
Left Scaphoid Bone
Left Scapula Or Shoulder Blade Bone
Anterior Medial Left Shoulder Skin
Anterior Midline Left Shoulder Skin
Anterior Lateral Left Shoulder Skin
Posterior Lateral Left Shoulder Skin
Posterior Midline Left Shoulder Skin
Posterior Medial Left Shoulder Skin
Left Small Intestine
Left Sphenoid Bone
Left Spleen Lymphoid Tissue
Left Spleen
Left Splenic Hilar Lymphoid Tissue
Left Stapes Bone
Left Stomach
Left Submandibular Lymphoid Tissue
Left Submental Lymphoid Tissue
Left Supraclavicular Lymphoid Tissue
Left Talus Bone
Left Temporal Bone
Left Testis
Left Thymic Lymphoid Tissue
Left Tibia Bone
Left Tonsils Lymphoid Tissue
Left Trapezium Bone
Left Trapezoid Bone
Left Triquetral Bone
Left Ulna Bone
Anterior Medial Left Upper Arm Skin
Anterior Midline Left Upper Arm Skin
Anterior Lateral Left Upper Arm Skin
Posterior Lateral Left Upper Arm Skin
Posterior Midline Left Upper Arm Skin
Posterior Medial Left Upper Arm Skin
Anterior Medial Left Upper Leg (Anterior And Posterior Thigh) Skin
Anterior Midline Left Upper Leg (Anterior And Posterior Thigh) Skin
Anterior Lateral Left Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Lateral Left Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Midline Left Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Medial Left Upper Leg (Anterior And Posterior Thigh) Skin
Left Vomer Bone
Left Waldeyer Ring Lymphoid Tissue
Anterior Medial Left Wrist Skin
Anterior Left Wrist Skin
Anterior Midline Left Wrist Skin
Anterior Lateral Left Wrist Skin
Posterior Lateral Left Wrist Skin
Posterior Midline Left Wrist Skin
Posterior Medial Left Wrist Skin
Left Zygomatic Bone
Anterior Midline Abdomen Skin
Midline Abdominal Lymphoid Tissue
Posterior Midline Back Skin
Midline Bladder
Posterior Midline Buttocks Skin
Midline Celiac Lymphoid Tissue
Anterior Midline Chest Skin
Anterior Midline Chin Skin
Midline Coccyx Bone
Midline Ethmoid Bone
Anterior Midline Forehead Skin
Midline Frontal Bone
Midline Gallbladder
Anterior Midline Genitalia Skin
Posterior Midline Genitalia Skin
Midline Heart
Midline Hilar Lymphoid Tissue
Midline Hyoid Bone
Midline Large Intestine
Anterior Midline Lip Skin
Midline Liver
Midline Mandible Bone
Midline Maxilla Bone
Midline Mesenteric Lymphoid Tissue
Anterior Midline Neck Skin
Posterior Midline Neck Skin
Anterior Midline Nose Skin
Midline Occipital Bone
Midline Ossa Coxae Bone
Midline Pancreas
Midline Paraaortic Lymphoid Tissue
Midline Porta Hepatis Lymphoid Tissue
Midline Retroperitoneal Lymphoid Tissue
Midline Sacrum Bone
Anterior Midline Scalp Skin
Posterior Midline Scalp Skin
Midline Small Intestine
Midline Sternum Bone
Midline Stomach
Anterior Lateral Right Abdomen Skin
Anterior Midline Right Abdomen Skin
Right Abdomen Skin
Anterior Medial Right Abdomen Skin
Right Abdominal Lymphoid Tissue
Right Adenoid Lymphoid Tissue
Right Adrenal
Anterior Lateral Right Ankle Skin
Anterior Midline Right Ankle Skin
Anterior Medial Right Ankle Skin
Posterior Medial Right Ankle Skin
Posterior Midline Right Ankle Skin
Posterior Lateral Right Ankle Skin
Right Axillary Lymphoid Tissue
Medial Right Back Skin
Midline Right Back Skin
Lateral Right Back Skin
Right Bladder
Right Brachial Lymphoid Tissue
Medial Right Buttocks Skin
Midline Right Buttocks Skin
Posterior Lateral Right Buttocks Skin
Right Calcaneus Bone
Right Capitate Bone
Right Celiac Lymphoid Tissue
Anterior Lateral Right Cheek Skin
Anterior Midline Right Cheek Skin
Anterior Medial Right Cheek Skin
Anterior Lateral Right Chest Skin
Anterior Midline Right Chest Skin
Anterior Medial Right Chest Skin
Anterior Lateral Right Chin Skin
Anterior Midline Right Chin Skin
Anterior Medial Right Chin Skin
Anterior Right Chin Skin
Right Clavicle Or Collarbone Bone
Right Cuboid Bone
Anterior Lateral Right Ear Skin
Anterior Midline Right Ear Skin
Anterior Medial Right Ear Skin
Posterior Medial Right Ear Skin
Posterior Lateral Right Ear Skin
Anterior Lateral Right Elbow Skin
Anterior Right Elbow Skin
Anterior Midline Right Elbow Skin
Anterior Medial Right Elbow Skin
Posterior Medial Right Elbow Skin
Posterior Midline Right Elbow Skin
Posterior Lateral Right Elbow Skin
Right Epitrochlear Lymphoid Tissue
Right Ethmoid Bone
Anterior Lateral Right Eyebrow Skin
Anterior Midline Right Eyebrow Skin
Anterior Medial Right Eyebrow Skin
Anterior Lateral Right Eyelid Skin
Anterior Midline Right Eyelid Skin
Anterior Medial Right Eyelid Skin
Right Femoral Lymphoid Tissue
Right Femur Bone
Right Fibula Bone
Anterior Lateral Right Foot And Toes Skin
Anterior Midline Right Foot And Toes Skin
Anterior Medial Right Foot And Toes Skin
Posterior Midline Right Foot And Toes Skin
Posterior Lateral Right Foot And Toes Skin
Right Foot Distal Phalange 1 Bone
Right Foot Distal Phalange 2 Bone
Right Foot Distal Phalange 3 Bone
Right Foot Distal Phalange 4 Bone
Right Foot Distal Phalange 5 Bone
Right Foot Middle Phalange 2 Bone
Right Foot Middle Phalange 3 Bone
Right Foot Middle Phalange 4 Bone
Right Foot Middle Phalange 5 Bone
Right Foot Proximal Phalange 1 Bone
Right Foot Proximal Phalange 2 Bone
Right Foot Proximal Phalange 3 Bone
Right Foot Proximal Phalange 4 Bone
Right Foot Proximal Phalange 5 Bone
Anterior Lateral Right Forearm Skin
Anterior Midline Right Forearm Skin
Anterior Medial Right Forearm Skin
Posterior Medial Right Forearm Skin
Posterior Midline Right Forearm Skin
Posterior Lateral Right Forearm Skin
Lateral Right Forehead Skin
Anterior Lateral Right Forehead Skin
Anterior Midline Right Forehead Skin
Anterior Medial Right Forehead Skin
Right Frontal Bone
Right Gallbladder
Anterior Lateral Right Genitalia Skin
Midline Right Genitalia Skin
Anterior Midline Right Genitalia Skin
Posterior Midline Right Genitalia Skin
Posterior Medial Right Genitalia Skin
Posterior Lateral Right Genitalia Skin
Right Hamate Bone
Anterior Lateral Right Hand And Fingers Skin
Anterior Midline Right Hand And Fingers Skin
Anterior Medial Right Hand And Fingers Skin
Posterior Medial Right Hand And Fingers Skin
Posterior Midline Right Hand And Fingers Skin
Posterior Lateral Right Hand And Fingers Skin
Right Hand Distal Phalange 1 Bone
Right Hand Distal Phalange 2 Bone
Right Hand Distal Phalange 3 Bone
Right Hand Distal Phalange 4 Bone
Right Hand Distal Phalange 5 Bone
Right Hand Middle Phalange 2 Bone
Right Hand Middle Phalange 3 Bone
Right Hand Middle Phalange 4 Bone
Right Hand Middle Phalange 5 Bone
Right Hand Proximal Phalange 1 Bone
Right Hand Proximal Phalange 2 Bone
Right Hand Proximal Phalange 3 Bone
Right Hand Proximal Phalange 4 Bone
Right Hand Proximal Phalange 5 Bone
Right Heart
Right Hilar Lymphoid Tissue
Right Humerus Bone
Right Iliac Lymphoid Tissue
Right Ilium Bone
Right Incus Bone
Right Inferior Nasal Conchae Bone
Right Infraclavicular Lymphoid Tissue
Right Inguinal Lymphoid Tissue
Right Intermediate Cuneiform Bone
Right Ischium Bone
Right Kidney
Anterior Lateral Right Knee Skin
Anterior Midline Right Knee Skin
Anterior Medial Right Knee Skin
Posterior Medial Right Knee Skin
Posterior Midline Right Knee Skin
Posterior Lateral Right Knee Skin
Right Lacrimal Bone
Right Large Intestine
Right Lateral Cuneiform Bone
Right Level Ii Cervical Lymphoid Tissue
Right Level Iii Cervical Lymphoid Tissue
Right Level Iv Cervical Lymphoid Tissue
Right Level V Cervical Lymphoid Tissue
Right Level Vi Cervical Lymphoid Tissue
Right Level Vii Cervical Lymphoid Tissue
Right Lingual Tonsils Lymphoid Tissue
Anterior Lateral Right Lip Skin
Anterior Midline Right Lip Skin
Anterior Medial Right Lip Skin
Right Liver
Anterior Lateral Right Lower Leg (Shin And Calf) Skin
Anterior Midline Right Lower Leg (Shin And Calf) Skin
Anterior Medial Right Lower Leg (Shin And Calf) Skin
Posterior Medial Right Lower Leg (Shin And Calf) Skin
Posterior Midline Right Lower Leg (Shin And Calf) Skin
Posterior Lateral Right Lower Leg (Shin And Calf) Skin
Right Lunate Bone
Right Lungs
Right Malleus Bone
Right Mandible Bone
Right Maxilla Bone
Right Medial Cuneiform Bone
Right Mesenteric Lymphoid Tissue
Right Metacarpal 1 Bone
Right Metacarpal 2 Bone
Right Metacarpal 3 Bone
Right Metacarpal 4 Bone
Right Metacarpal 5 Bone
Right Metatarsal 1 Bone
Right Metatarsal 2 Bone
Right Metatarsal 3 Bone
Right Metatarsal 4 Bone
Right Metatarsal 5 Bone
Right Nasal Bone
Right Nasopharynx Lymphoid Tissue
Right Navicular Bone
Anterior Lateral Right Neck Skin
Anterior Right Neck Skin
Anterior Midline Right Neck Skin
Anterior Medial Right Neck Skin
Posterior Medial Right Neck Skin
Posterior Midline Right Neck Skin
Posterior Lateral Right Neck Skin
Anterior Lateral Right Nose Skin
Anterior Medial Right Nose Skin
Anterior Midline Right Nose Skin
Right Occipital Lymphoid Tissue
Right Occipital Bone
Right Ossa Coxae Bone
Right Ovary
Right Palatine Bone
Right Pancreas
Right Paraaortic Lymphoid Tissue
Right Parietal Bone
Right Parotid Lymphoid Tissue
Right Patella Bone
Right Pectoral Lymphoid Tissue
Right Peritracheal Lymphoid Tissue
Right Pisiform Bone
Right Popliteal Lymphoid Tissue
Right Porta Hepatis Lymphoid Tissue
Right Preauricular Lymphoid Tissue
Right Pubis Bone
Right Radius Bone
Right Retroperitoneal Lymphoid Tissue
Right Rib 1 Bone
Right Rib 10 Bone
Right Rib 11 Bone
Right Rib 12 Bone
Right Rib 2 Bone
Right Rib 3 Bone
Right Rib 4 Bone
Right Rib 5 Bone
Right Rib 6 Bone
Right Rib 7 Bone
Right Rib 8 Bone
Right Rib 9 Bone
Anterior Lateral Right Scalp Skin
Anterior Midline Right Scalp Skin
Anterior Medial Right Scalp Skin
Posterior Medial Right Scalp Skin
Posterior Midline Right Scalp Skin
Posterior Lateral Right Scalp Skin
Right Scaphoid Bone
Right Scapula Or Shoulder Blade Bone
Anterior Lateral Right Shoulder Skin
Anterior Midline Right Shoulder Skin
Anterior Medial Right Shoulder Skin
Posterior Medial Right Shoulder Skin
Posterior Midline Right Shoulder Skin
Posterior Lateral Right Shoulder Skin
Right Small Intestine
Right Sphenoid Bone
Right Spleen Lymphoid Tissue
Right Spleen
Right Splenic Hilar Lymphoid Tissue
Right Stapes Bone
Right Stomach
Right Submandibular Lymphoid Tissue
Right Submental Lymphoid Tissue
Right Supraclavicular Lymphoid Tissue
Right Talus Bone
Right Temporal Bone
Right Testis
Right Thymic Lymphoid Tissue
Right Tibia Bone
Right Tonsils Lymphoid Tissue
Right Trapezium Bone
Right Trapezoid Bone
Right Triquetral Bone
Right Ulna Bone
Anterior Lateral Right Upper Arm Skin
Anterior Midline Right Upper Arm Skin
Anterior Medial Right Upper Arm Skin
Posterior Medial Right Upper Arm Skin
Posterior Midline Right Upper Arm Skin
Posterior Lateral Right Upper Arm Skin
Anterior Lateral Right Upper Leg (Anterior And Posterior Thigh) Skin
Anterior Midline Right Upper Leg (Anterior And Posterior Thigh) Skin
Anterior Medial Right Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Medial Right Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Midline Right Upper Leg (Anterior And Posterior Thigh) Skin
Posterior Lateral Right Upper Leg (Anterior And Posterior Thigh) Skin
Right Vomer Bone
Right Waldeyer Ring Lymphoid Tissue
Anterior Lateral Right Wrist Skin
Anterior Midline Right Wrist Skin
Anterior Medial Right Wrist Skin
Posterior Medial Right Wrist Skin
Posterior Midline Right Wrist Skin
Posterior Lateral Right Wrist Skin
Right Zygomatic Bone
Abdomen Skin
Abdominal Lymphoid Tissue
Adenoid Lymphoid Tissue
Anus
Back Skin
Bladder
Brain
Buttocks Skin
Celiac Lymphoid Tissue
Cerebrospinal Fluid
Cervical Vertebrae 1 Bone
Cervical Vertebrae 2 Bone
Cervical Vertebrae 3 Bone
Cervical Vertebrae 4 Bone
Cervical Vertebrae 5 Bone
Cervical Vertebrae 6 Bone
Cervical Vertebrae 7 Bone
Cervix
Chest Skin
Chin Skin
Esophagus
Forehead Skin
Gallbladder
Genitalia Skin
Heart
Hilar Lymphoid Tissue
Large Intestine
Leptomeningeal
Lingual Tonsils Lymphoid Tissue
Lip Skin
Liver
Lumbar Vertebrae 1 Bone
Lumbar Vertebrae 2 Bone
Lumbar Vertebrae 3 Bone
Lumbar Vertebrae 4 Bone
Lumbar Vertebrae 5 Bone
Mesenteric Lymphoid Tissue
Nasal Mucosa
Nasopharynx Lymphoid Tissue
Neck Skin
Posterior Neck Skin
Nose Skin
Oral Mucosa
Pancreas
Paraaortic Lymphoid Tissue
Porta Hepatis Lymphoid Tissue
Retroperitoneal Lymphoid Tissue
Scalp Skin
Posterior Scalp Skin
Small Intestine
Spinal Cord
Spleen Lymphoid Tissue
Stomach
Thoracic Vertebrae 1 Bone
Thoracic Vertebrae 10 Bone
Thoracic Vertebrae 11 Bone
Thoracic Vertebrae 12 Bone
Thoracic Vertebrae 2 Bone
Thoracic Vertebrae 3 Bone
Thoracic Vertebrae 4 Bone
Thoracic Vertebrae 5 Bone
Thoracic Vertebrae 6 Bone
Thoracic Vertebrae 7 Bone
Thoracic Vertebrae 8 Bone
Thoracic Vertebrae 9 Bone
Tonsils Lymphoid Tissue
Vagina
Waldeyer Ring Lymphoid Tissue


Serial Measurements of Cancer Lesions

Capturing measurements of tumor size over time is critical to gain insight about the natural history of a malignancy, as well as its response to treatment. The LII permits the collection of one-, two- or three-dimensional tumor measurements obtained over time. Due to variations in unit collections, and to minimize errors in conversions from millimeters and centimeters, the LII incorporates a units field to accompany each time point of collection.

Response to Treatment

Capturing clinical tumor characteristics with the LII can also allow for the response to a variety of therapeutic modalities applied to that lesion. In addition to collecting tumor measurements over time, the LII allows for the storage of clinical photographs, taken during the patient journey. For certain types of malignancies, e.g. cutaneous malignancies, clinical photography has played an important role in response assessment. Due to the clinical tumor characteristics of cutaneous lesions, reliable radiographic evaluation is not always possible. Consequently, visual assessment and digital photographic evaluation have played important roles in recent pivotal trials for therapies approved for skin cancer8. Therefore, incorporating clinical photographs in patient-level data collection has the potential to expand the utility of RWD. Furthermore, the LII captures whether or not the lesion was ever rendered “No Evidence of Disease (NED)”, and the date of NED, if obtained. Thus, when paired with additional data collection instruments, such as an Imaging Instrument6 which captures radiographical measurements of tumor lesions, the LII can be part of a comprehensive documentation of tumor response to treatment. For example, the Lesion Information instrument was used in our real-world assessment of response to anti-PD1 therapy in advanced cutaneous squamous cell carcinoma.9

Data Visualization of Lesion Information

Structured data collection of clinical tumor characteristics provides an opportunity for data visualizations that can be used for data quality examinations as well as exploratory data analyses. The LII DCI can be paired with external integrated development environments, such as RStudio®10, to generate a variety of data visualizations. We previously published a REDCap®-to-R pipeline for interactive Body Map visualization using core features of the LII11. When paired with graphical software (e.g. ggplot212), structured DCIs such as the LII can become part of a clinical informatics pipeline that yield data visualizations with the ability to provide clinically relevant insights. For example in rare diseases where the patterns of metastatic spread have not been comprehensibly described, graphics such as Figure 2 can be generated over a cohort of patients and may provide an improved understanding of the natural history of the disease. In another example, we used such a pipeline to visualize the anatomic distribution and pre-biopsy clinical impressions of primary Merkel cell carcinoma tumors13
Figure 2: Metastatic Spread of Merkel Cell Carcinoma in a Single Patient

Figure 2: Metastatic Spread of Merkel Cell Carcinoma in a Single Patient. Depicted is a example of a single patient with Merkel Cell Carcinoma, with the landscape of lesions over the patient’s journey captured with the LII. The graphic created with a template from BioRender and overlaid with a plot from ggplot2. The coordinates for the anatomical locations of the tumor lesions are a custom design, as described previously11. Anatomical images created with BioRender.com.

Limitations and Solutions

The LII was designed to be incorporated into a REDCAp® project. Therefore, its current build is easily extensible to existing REDCAp® projects. However, investigators utilizing other electronic data capture systems will have to modify the provided data dictionary to adapt to their clinical research platform. Furthermore, the version of the data dictionary provided is customized for the Merkel Cell Carcinoma Patient Registry. Consequently, there a few clinical tumor characteristics idiosyncratic to MCC (e.g. the variable tum_type contains the choice “MCC of Unknown Primary (non-cutaneous lesion at initial presentation)”). However, because the data dictionary is a csv file, individual investigators can modify the LII as needed for their disease of interest.

In addition, if an investigator has incorporated a lesion field that uses other common anatomical coding systems, such as the International Classification of Diseases for Oncology, 3rd edition (ICD-O-3) or the Systematized Nomenclature of Medicine (SNOMED), we have incorporated a lookup table that converts these fields into coordinates on the BodyMapR Body Map (Table 3).

Table 3: ICD-O-3 and SNOMED Lookup Tables
Anatomic Structure ICD-O-3 Code SNOMED
Anterior Medial Left Abdomen Skin C44.5 181491009
Anterior Midline Left Abdomen Skin C44.5 181491009
Anterior Lateral Left Abdomen Skin C44.5 699906008
Left Abdominal Lymphoid Tissue C77.2 818991007
Left Adenoid Lymphoid Tissue C11.1 781383005
Left Adrenal C74.9 12003004
Anterior Medial Left Ankle Skin C44.7 771124004
Anterior Midline Left Ankle Skin C44.7 771124004
Anterior Lateral Left Ankle Skin C44.7 771124004
Posterior Lateral Left Ankle Skin C44.7 771124004
Posterior Midline Left Ankle Skin C44.7 771124004
Posterior Medial Left Ankle Skin C44.7 771124004
Left Axillary Lymphoid Tissue C77.3 746225004
Posterior Lateral Left Back Skin C44.5 66643007
Midline Left Back Skin C44.5 66643007
Posterior Medial Left Back Skin C44.5 66643007
Medial Left Back Skin C44.5 66643007
Left Bladder C67.9 89837001
Left Brachial Lymphoid Tissue C77.3 33770006
Posterior Lateral Left Buttocks Skin C44.5 723979003
Midline Left Buttocks Skin C44.5 723979003
Posterior Medial Left Buttocks Skin C44.5 723979003
Left Buttocks Skin C44.5 723979003
Medial Left Buttocks Skin C44.5 723979003
Left Calcaneus Bone C40.3 722735002
Left Capitate Bone C40.1 764658006
Left Celiac Lymphoid Tissue C77.2 47985009
Anterior Medial Left Cheek Skin C44.3 36141000
Anterior Midline Left Cheek Skin C44.3 36141000
Anterior Lateral Left Cheek Skin C44.3 36141000
Anterior Medial Left Chest Skin C44.5 789221006
Anterior Midline Left Chest Skin C44.5 789221006
Anterior Lateral Left Chest Skin C44.5 789221006
Anterior Medial Left Chin Skin C44.3 281718000
Anterior Midline Left Chin Skin C44.3 281718000
Anterior Lateral Left Chin Skin C44.3 281718000
Left Clavicle Or Collarbone Bone C41.3 720617006
Left Cuboid Bone C40.3 764464007
Anterior Medial Left Ear Skin C44.2 761965001
Anterior Lateral Left Ear Skin C44.2 761965001
Posterior Medial Left Ear Skin C44.2 761965001
Posterior Lateral Left Ear Skin C44.2 761965001
Posterior Midline Left Ear Skin C44.2 761965001
Anterior Medial Left Elbow Skin C44.6 770847008
Anterior Midline Left Elbow Skin C44.6 770847008
Anterior Lateral Left Elbow Skin C44.6 770847008
Posterior Lateral Left Elbow Skin C44.6 770847008
Posterior Midline Left Elbow Skin C44.6 770847008
Posterior Medial Left Elbow Skin C44.6 770847008
Left Epitrochlear Lymphoid Tissue C77.3 28870006
Left Ethmoid Bone C41.0 119526004
Anterior Medial Left Eyebrow Skin C44.3 367577003
Anterior Midline Left Eyebrow Skin C44.3 367577003
Anterior Lateral Left Eyebrow Skin C44.3 367577003
Anterior Medial Left Eyelid Skin C44.3 719882004
Anterior Midline Left Eyelid Skin C44.3 719882004
Anterior Lateral Left Eyelid Skin C44.3 719882004
Left Femoral Lymphoid Tissue C77.4 279802007
Left Femur Bone C40.2 722738000
Left Fibula Bone C40.2 724231006
Anterior Medial Left Foot And Toes Skin C44.7 761968004
Anterior Midline Left Foot And Toes Skin C44.7 761968004
Anterior Lateral Left Foot And Toes Skin C44.7 761968004
Posterior Lateral Left Foot And Toes Skin C44.7 761974004
Posterior Midline Left Foot And Toes Skin C44.7 761974004
Left Foot Distal Phalange 1 Bone C40.3 720662005
Left Foot Distal Phalange 2 Bone C40.3 720656000
Left Foot Distal Phalange 3 Bone C40.3 720656000
Left Foot Distal Phalange 4 Bone C40.3 720656000
Left Foot Distal Phalange 5 Bone C40.3 720656000
Left Foot Middle Phalange 2 Bone C40.3 720654002
Left Foot Middle Phalange 3 Bone C40.3 720654002
Left Foot Middle Phalange 4 Bone C40.3 720654002
Left Foot Middle Phalange 5 Bone C40.3 720654002
Left Foot Proximal Phalange 1 Bone C40.3 720661003
Left Foot Proximal Phalange 2 Bone C40.3 720652003
Left Foot Proximal Phalange 3 Bone C40.3 720652003
Left Foot Proximal Phalange 4 Bone C40.3 720652003
Left Foot Proximal Phalange 5 Bone C40.3 720652003
Anterior Medial Left Forearm Skin C44.6 764707001
Anterior Midline Left Forearm Skin C44.6 764707001
Anterior Lateral Left Forearm Skin C44.6 764707001
Posterior Lateral Left Forearm Skin C44.6 764707001
Posterior Midline Left Forearm Skin C44.6 764707001
Posterior Medial Left Forearm Skin C44.6 764707001
Anterior Medial Left Forehead Skin C44.3 68698007
Anterior Midline Left Forehead Skin C44.3 68698007
Lateral Left Forehead Skin C44.3 68698007
Anterior Lateral Left Forehead Skin C44.3 68698007
Left Frontal Bone C41.0 74872008
Left Gallbladder C23.9 28231008
Anterior Medial Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Anterior Midline Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Midline Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Lateral Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Midline Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Medial Left Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Left Hamate Bone C40.1 764746004
Anterior Medial Left Hand And Fingers Skin C44.6 782451002
Anterior Midline Left Hand And Fingers Skin C44.6 782451002
Anterior Lateral Left Hand And Fingers Skin C44.6 782451002
Posterior Lateral Left Hand And Fingers Skin C44.6 789136004
Posterior Midline Left Hand And Fingers Skin C44.6 789136004
Posterior Medial Left Hand And Fingers Skin C44.6 789136004
Left Hand Distal Phalange 1 Bone C40.1 762866004
Left Hand Distal Phalange 2 Bone C40.1 762858008
Left Hand Distal Phalange 3 Bone C40.1 762858008
Left Hand Distal Phalange 4 Bone C40.1 762846008
Left Hand Distal Phalange 5 Bone C40.1 762836006
Left Hand Middle Phalange 2 Bone C40.1 762862002
Left Hand Middle Phalange 3 Bone C40.1 762850001
Left Hand Middle Phalange 4 Bone C40.1 762844006
Left Hand Middle Phalange 5 Bone C40.1 762838007
Left Hand Proximal Phalange 1 Bone C40.1 762868003
Left Hand Proximal Phalange 2 Bone C40.1 762860005
Left Hand Proximal Phalange 3 Bone C40.1 762854005
Left Hand Proximal Phalange 4 Bone C40.1 762842005
Left Hand Proximal Phalange 5 Bone C40.1 762840002
Left Heart C38.0 17398003
Left Hilar Lymphoid Tissue C77.1 53074004
Left Humerus Bone C40.0 719460003
Left Iliac Lymphoid Tissue C77.5 84219008
Left Ilium Bone C41.4 773840006
Left Incus Bone C30.1 35395007
Left Inferior Nasal Conchae Bone C41.0 118648008
Left Infraclavicular Lymphoid Tissue C77.3 9659009
Left Inguinal Lymphoid Tissue C77.4 8928004
Left Intermediate Cuneiform Bone C40.3 764556003
Left Ischium Bone NA NA
Left Kidney C64.9 18639004
Anterior Medial Left Knee Skin C44.7 726002000
Anterior Midline Left Knee Skin C44.7 726002000
Anterior Lateral Left Knee Skin C44.7 726002000
Posterior Lateral Left Knee Skin C44.7 726002000
Posterior Midline Left Knee Skin C44.7 726002000
Posterior Medial Left Knee Skin C44.7 726002000
Left Lacrimal Bone C41.0 6229007
Left Large Intestine C18.9 14742008
Left Lateral Cuneiform Bone C40.3 764748003
Left Level Ii Cervical Lymphoid Tissue C77.0 245321008
Left Level Iii Cervical Lymphoid Tissue C77.0 245322001
Left Level Iv Cervical Lymphoid Tissue C77.0 245323006
Left Level V Cervical Lymphoid Tissue C77.0 245324000
Left Level Vi Cervical Lymphoid Tissue C77.0 168460001
Left Level Vii Cervical Lymphoid Tissue C77.0 127925003
Left Lingual Tonsils Lymphoid Tissue C02.4 2048000
Anterior Medial Left Lip Skin C44.0 88089004
Anterior Lateral Left Lip Skin C44.0 88089004
Anterior Midline Left Lip Skin C44.0 88089004
Left Liver C22.0 69842003
Anterior Medial Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Anterior Midline Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Anterior Lateral Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Posterior Lateral Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Posterior Midline Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Posterior Medial Left Lower Leg (Shin And Calf) Skin C44.7 723972007
Left Lunate Bone C40.1 737403003
Left Lungs C34.9 44029006
Left Malleus Bone C30.1 420329002
Left Mandible Bone C41.1 782962006
Left Maxilla Bone C41.0 773937007
Left Medial Cuneiform Bone C40.3 764752003
Left Mesenteric Lymphoid Tissue C77.2 279795009
Left Metacarpal 1 Bone C40.1 762016006
Left Metacarpal 2 Bone C40.1 762033004
Left Metacarpal 3 Bone C40.1 762041004
Left Metacarpal 4 Bone C40.1 762027008
Left Metacarpal 5 Bone C40.1 762010000
Left Metatarsal 1 Bone C40.3 761978001
Left Metatarsal 2 Bone C40.3 737448004
Left Metatarsal 3 Bone C40.3 773720006
Left Metatarsal 4 Bone C40.3 773808007
Left Metatarsal 5 Bone C40.3 773811008
Left Nasal Bone C41.0 74386004
Left Nasopharynx Lymphoid Tissue C11.1 781383005
Left Navicular Bone C40.3 723633005
Anterior Medial Left Neck Skin C44.4 699912003
Anterior Midline Left Neck Skin C44.4 699912003
Anterior Lateral Left Neck Skin C44.4 244104000
Posterior Lateral Left Neck Skin C44.4 244105004
Posterior Midline Left Neck Skin C44.4 699912003
Posterior Medial Left Neck Skin C44.4 699912003
Anterior Medial Left Nose Skin C44.3 244089006
Anterior Midline Left Nose Skin C44.3 314394005
Anterior Lateral Left Nose Skin C44.3 244089006
Left Occipital Lymphoid Tissue C77.0 3916005
Left Occipital Bone C41.0 787063005
Left Ossa Coxae Bone C41.4 28254004
Left Ovary C56.9 43981004
Left Palatine Bone C41.0 51283005
Left Pancreas C25.9 73239005
Left Paraaortic Lymphoid Tissue C77.2 245285004
Left Parietal Bone C41.0 24924006
Left Parotid Lymphoid Tissue C77.0 44178003
Left Patella Bone C40.3 734208001
Left Pectoral Lymphoid Tissue C77.3 69691007
Left Peritracheal Lymphoid Tissue C77.1 127936005
Left Pisiform Bone C40.1 764702007
Left Popliteal Lymphoid Tissue C77.4 47471008
Left Porta Hepatis Lymphoid Tissue C77.2 61492009
Left Preauricular Lymphoid Tissue C77.0 25247006
Left Pubis Bone C41.4 734356009
Left Radius Bone C40.0 719464007
Left Retroperitoneal Lymphoid Tissue C77.2 91394001
Left Rib 1 Bone C41.3 48535007
Left Rib 10 Bone C41.3 77644006
Left Rib 11 Bone C41.3 58830002
Left Rib 12 Bone C41.3 43993008
Left Rib 2 Bone C41.3 78247007
Left Rib 3 Bone C41.3 25888004
Left Rib 4 Bone C41.3 25523003
Left Rib 5 Bone C41.3 15339008
Left Rib 6 Bone C41.3 59558009
Left Rib 7 Bone C41.3 24915002
Left Rib 8 Bone C41.3 5953002
Left Rib 9 Bone C41.3 22565002
Anterior Medial Left Scalp Skin C44.4 699900002
Anterior Midline Left Scalp Skin C44.4 699900002
Anterior Lateral Left Scalp Skin C44.4 699900002
Posterior Lateral Left Scalp Skin C44.4 61719002
Posterior Medial Left Scalp Skin C44.4 61719002
Posterior Midline Left Scalp Skin C44.4 61719002
Left Scaphoid Bone C40.1 724196009
Left Scapula Or Shoulder Blade Bone C40.0 719627005
Anterior Medial Left Shoulder Skin C44.6 771101006
Anterior Midline Left Shoulder Skin C44.6 771101006
Anterior Lateral Left Shoulder Skin C44.6 771101006
Posterior Lateral Left Shoulder Skin C44.6 771101006
Posterior Midline Left Shoulder Skin C44.6 771101006
Posterior Medial Left Shoulder Skin C44.6 771101006
Left Small Intestine C17.9 30315005
Left Sphenoid Bone C41.0 73117003
Left Spleen Lymphoid Tissue C42.2 78961009
Left Spleen C42.2 78961009
Left Splenic Hilar Lymphoid Tissue C77.2 280824006
Left Stapes Bone C30.1 22718006
Left Stomach C16.9 69695003
Left Submandibular Lymphoid Tissue C77.0 59503006
Left Submental Lymphoid Tissue C77.0 46055009
Left Supraclavicular Lymphoid Tissue C77.0 76838003
Left Talus Bone C40.3 737405005
Left Temporal Bone C41.0 763817008
Left Testis C62.9 63239009
Left Thymic Lymphoid Tissue C37.9 9875009
Left Tibia Bone C40.2 719492002
Left Tonsils Lymphoid Tissue C09.9 15058008
Left Trapezium Bone C40.1 764661007
Left Trapezoid Bone C40.1 787049004
Left Triquetral Bone C40.1 764825000
Left Ulna Bone C40.0 719615007
Anterior Medial Left Upper Arm Skin C44.6 788805003
Anterior Midline Left Upper Arm Skin C44.6 788805003
Anterior Lateral Left Upper Arm Skin C44.6 788805003
Posterior Lateral Left Upper Arm Skin C44.6 788805003
Posterior Midline Left Upper Arm Skin C44.6 788805003
Posterior Medial Left Upper Arm Skin C44.6 788805003
Anterior Medial Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Anterior Midline Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Anterior Lateral Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Posterior Lateral Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Posterior Midline Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Posterior Medial Left Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774103008
Left Vomer Bone C41.0 87166008
Left Waldeyer Ring Lymphoid Tissue C14.2 17861009
Anterior Medial Left Wrist Skin C44.6 24527008
Anterior Left Wrist Skin C44.6 24527008
Anterior Midline Left Wrist Skin C44.6 24527008
Anterior Lateral Left Wrist Skin C44.6 244157004
Posterior Lateral Left Wrist Skin C44.6 244157004
Posterior Midline Left Wrist Skin C44.6 52876008
Posterior Medial Left Wrist Skin C44.6 52876008
Left Zygomatic Bone C41.0 787058006
Anterior Midline Abdomen Skin C44.5 181491009
Midline Abdominal Lymphoid Tissue C77.2 818991007
Posterior Midline Back Skin C44.5 66643007
Midline Bladder C67.9 89837001
Posterior Midline Buttocks Skin C44.5 22180002
Midline Celiac Lymphoid Tissue C77.2 47985009
Anterior Midline Chest Skin C44.5 74160004
Anterior Midline Chin Skin C44.3 281718000
Midline Coccyx Bone C41.4 64688005
Midline Ethmoid Bone C41.0 119526004
Anterior Midline Forehead Skin C44.3 68698007
Midline Frontal Bone C41.0 74872008
Midline Gallbladder C23.9 28231008
Anterior Midline Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Midline Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Midline Heart C38.0 80891009
Midline Hilar Lymphoid Tissue C77.1 53074004
Midline Hyoid Bone C41.0 21387005
Midline Large Intestine C18.9 14742008
Anterior Midline Lip Skin C44.0 88089004
Midline Liver C22.0 71133005
Midline Mandible Bone C41.1 91609006
Midline Maxilla Bone C41.0 70925003
Midline Mesenteric Lymphoid Tissue C77.2 279795009
Anterior Midline Neck Skin C44.4 281720002
Posterior Midline Neck Skin C44.4 4658004
Anterior Midline Nose Skin C44.3 314394005
Midline Occipital Bone C41.0 31640002
Midline Ossa Coxae Bone C41.4 28254004
Midline Pancreas C25.9 40133006
Midline Paraaortic Lymphoid Tissue C77.2 245285004
Midline Porta Hepatis Lymphoid Tissue C77.2 61492009
Midline Retroperitoneal Lymphoid Tissue C77.2 91394001
Midline Sacrum Bone C41.4 699698002
Anterior Midline Scalp Skin C44.4 699900002
Posterior Midline Scalp Skin C44.4 61719002
Midline Small Intestine C17.9 30315005
Midline Sternum Bone C41.3 56873002
Midline Stomach C16.9 69695003
Anterior Lateral Right Abdomen Skin C44.5 699906008
Anterior Midline Right Abdomen Skin C44.5 181491009
Right Abdomen Skin C44.5 86381001
Anterior Medial Right Abdomen Skin C44.5 181491009
Right Abdominal Lymphoid Tissue C77.2 818991007
Right Adenoid Lymphoid Tissue C11.1 781384004
Right Adrenal C74.9 29392005
Anterior Lateral Right Ankle Skin C44.7 771125003
Anterior Midline Right Ankle Skin C44.7 771125003
Anterior Medial Right Ankle Skin C44.7 771125003
Posterior Medial Right Ankle Skin C44.7 771125003
Posterior Midline Right Ankle Skin C44.7 771125003
Posterior Lateral Right Ankle Skin C44.7 771125003
Right Axillary Lymphoid Tissue C77.3 746224000
Medial Right Back Skin C44.5 66643007
Midline Right Back Skin C44.5 66643007
Lateral Right Back Skin C44.5 66643007
Right Bladder C67.9 119221008
Right Brachial Lymphoid Tissue C77.3 33770006
Medial Right Buttocks Skin C44.5 723980000
Midline Right Buttocks Skin C44.5 723980000
Posterior Lateral Right Buttocks Skin C44.5 723980000
Right Calcaneus Bone C40.3 722736001
Right Capitate Bone C40.1 764659003
Right Celiac Lymphoid Tissue C77.2 47985009
Anterior Lateral Right Cheek Skin C44.3 36141000
Anterior Midline Right Cheek Skin C44.3 36141000
Anterior Medial Right Cheek Skin C44.3 36141000
Anterior Lateral Right Chest Skin C44.5 789222004
Anterior Midline Right Chest Skin C44.5 789222004
Anterior Medial Right Chest Skin C44.5 789222004
Anterior Lateral Right Chin Skin C44.3 281718000
Anterior Midline Right Chin Skin C44.3 281718000
Anterior Medial Right Chin Skin C44.3 281718000
Anterior Right Chin Skin C44.3 281718000
Right Clavicle Or Collarbone Bone C41.3 720616002
Right Cuboid Bone C40.3 764465008
Anterior Lateral Right Ear Skin C44.2 720985009
Anterior Midline Right Ear Skin C44.2 720985009
Anterior Medial Right Ear Skin C44.2 720985009
Posterior Medial Right Ear Skin C44.2 720985009
Posterior Lateral Right Ear Skin C44.2 720985009
Anterior Lateral Right Elbow Skin C44.6 770848003
Anterior Right Elbow Skin C44.6 770848003
Anterior Midline Right Elbow Skin C44.6 770848003
Anterior Medial Right Elbow Skin C44.6 770848003
Posterior Medial Right Elbow Skin C44.6 770848003
Posterior Midline Right Elbow Skin C44.6 770848003
Posterior Lateral Right Elbow Skin C44.6 770848003
Right Epitrochlear Lymphoid Tissue C77.3 770848003
Right Ethmoid Bone C41.0 119526004
Anterior Lateral Right Eyebrow Skin C44.3 367577003
Anterior Midline Right Eyebrow Skin C44.3 367577003
Anterior Medial Right Eyebrow Skin C44.3 367577003
Anterior Lateral Right Eyelid Skin C44.3 719881006
Anterior Midline Right Eyelid Skin C44.3 719881006
Anterior Medial Right Eyelid Skin C44.3 719881006
Right Femoral Lymphoid Tissue C77.4 279802007
Right Femur Bone C40.2 722739008
Right Fibula Bone C40.2 724230007
Anterior Lateral Right Foot And Toes Skin C44.7 761969007
Anterior Midline Right Foot And Toes Skin C44.7 761969007
Anterior Medial Right Foot And Toes Skin C44.7 761969007
Posterior Midline Right Foot And Toes Skin C44.7 761975003
Posterior Lateral Right Foot And Toes Skin C44.7 761975003
Right Foot Distal Phalange 1 Bone C40.3 720660002
Right Foot Distal Phalange 2 Bone C40.3 720655001
Right Foot Distal Phalange 3 Bone C40.3 720655001
Right Foot Distal Phalange 4 Bone C40.3 720655001
Right Foot Distal Phalange 5 Bone C40.3 720655001
Right Foot Middle Phalange 2 Bone C40.3 720653008
Right Foot Middle Phalange 3 Bone C40.3 720653008
Right Foot Middle Phalange 4 Bone C40.3 720653008
Right Foot Middle Phalange 5 Bone C40.3 720653008
Right Foot Proximal Phalange 1 Bone C40.3 720659007
Right Foot Proximal Phalange 2 Bone C40.3 720651005
Right Foot Proximal Phalange 3 Bone C40.3 720651005
Right Foot Proximal Phalange 4 Bone C40.3 720651005
Right Foot Proximal Phalange 5 Bone C40.3 720651005
Anterior Lateral Right Forearm Skin C44.6 764708006
Anterior Midline Right Forearm Skin C44.6 764708006
Anterior Medial Right Forearm Skin C44.6 764708006
Posterior Medial Right Forearm Skin C44.6 764708006
Posterior Midline Right Forearm Skin C44.6 764708006
Posterior Lateral Right Forearm Skin C44.6 764708006
Lateral Right Forehead Skin C44.3 68698007
Anterior Lateral Right Forehead Skin C44.3 68698007
Anterior Midline Right Forehead Skin C44.3 68698007
Anterior Medial Right Forehead Skin C44.3 68698007
Right Frontal Bone C41.0 74872008
Right Gallbladder C23.9 28231008
Anterior Lateral Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Midline Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Anterior Midline Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Midline Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Medial Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Posterior Lateral Right Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Right Hamate Bone C40.1 764747008
Anterior Lateral Right Hand And Fingers Skin C44.6 782450001
Anterior Midline Right Hand And Fingers Skin C44.6 782450001
Anterior Medial Right Hand And Fingers Skin C44.6 782450001
Posterior Medial Right Hand And Fingers Skin C44.6 789137008
Posterior Midline Right Hand And Fingers Skin C44.6 789137008
Posterior Lateral Right Hand And Fingers Skin C44.6 789137008
Right Hand Distal Phalange 1 Bone C40.1 762867008
Right Hand Distal Phalange 2 Bone C40.1 762865000
Right Hand Distal Phalange 3 Bone C40.1 762859000
Right Hand Distal Phalange 4 Bone C40.1 762847004
Right Hand Distal Phalange 5 Bone C40.1 762837002
Right Hand Middle Phalange 2 Bone C40.1 762863007
Right Hand Middle Phalange 3 Bone C40.1 762857003
Right Hand Middle Phalange 4 Bone C40.1 762845007
Right Hand Middle Phalange 5 Bone C40.1 762839004
Right Hand Proximal Phalange 1 Bone C40.1 762869006
Right Hand Proximal Phalange 2 Bone C40.1 762861009
Right Hand Proximal Phalange 3 Bone C40.1 762855006
Right Hand Proximal Phalange 4 Bone C40.1 762843000
Right Hand Proximal Phalange 5 Bone C40.1 762841003
Right Heart C38.0 79561009
Right Hilar Lymphoid Tissue C77.1 53074004
Right Humerus Bone C40.0 719461004
Right Iliac Lymphoid Tissue C77.5 84219008
Right Ilium Bone C41.4 773841005
Right Incus Bone C30.1 35395007
Right Inferior Nasal Conchae Bone C41.0 118648008
Right Infraclavicular Lymphoid Tissue C77.3 9659009
Right Inguinal Lymphoid Tissue C77.4 8928004
Right Intermediate Cuneiform Bone C40.3 764557007
Right Ischium Bone NA NA
Right Kidney C64.9 9846003
Anterior Lateral Right Knee Skin C44.7 726003005
Anterior Midline Right Knee Skin C44.7 726003005
Anterior Medial Right Knee Skin C44.7 726003005
Posterior Medial Right Knee Skin C44.7 726003005
Posterior Midline Right Knee Skin C44.7 726003005
Posterior Lateral Right Knee Skin C44.7 726003005
Right Lacrimal Bone C41.0 6229007
Right Large Intestine C18.9 14742008
Right Lateral Cuneiform Bone C40.3 764749006
Right Level Ii Cervical Lymphoid Tissue C77.0 245321008
Right Level Iii Cervical Lymphoid Tissue C77.0 245322001
Right Level Iv Cervical Lymphoid Tissue C77.0 245323006
Right Level V Cervical Lymphoid Tissue C77.0 245324000
Right Level Vi Cervical Lymphoid Tissue C77.0 168460001
Right Level Vii Cervical Lymphoid Tissue C77.0 127925003
Right Lingual Tonsils Lymphoid Tissue C02.4 2048000
Anterior Lateral Right Lip Skin C44.0 88089004
Anterior Midline Right Lip Skin C44.0 88089004
Anterior Medial Right Lip Skin C44.0 88089004
Right Liver C22.0 48521005
Anterior Lateral Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Anterior Midline Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Anterior Medial Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Posterior Medial Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Posterior Midline Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Posterior Lateral Right Lower Leg (Shin And Calf) Skin C44.7 723971000
Right Lunate Bone C40.1 737404009
Right Lungs C34.9 3341006
Right Malleus Bone C30.1 420329002
Right Mandible Bone C41.1 782963001
Right Maxilla Bone C41.0 773936003
Right Medial Cuneiform Bone C40.3 764753008
Right Mesenteric Lymphoid Tissue C77.2 279795009
Right Metacarpal 1 Bone C40.1 762017002
Right Metacarpal 2 Bone C40.1 762035006
Right Metacarpal 3 Bone C40.1 762042006
Right Metacarpal 4 Bone C40.1 762028003
Right Metacarpal 5 Bone C40.1 762011001
Right Metatarsal 1 Bone C40.3 761979009
Right Metatarsal 2 Bone C40.3 737447009
Right Metatarsal 3 Bone C40.3 773721005
Right Metatarsal 4 Bone C40.3 773809004
Right Metatarsal 5 Bone C40.3 773810009
Right Nasal Bone C41.0 74386004
Right Nasopharynx Lymphoid Tissue C11.1 781384004
Right Navicular Bone C40.3 723550002
Anterior Lateral Right Neck Skin C44.4 244104000
Anterior Right Neck Skin C44.4 699929000
Anterior Midline Right Neck Skin C44.4 699929000
Anterior Medial Right Neck Skin C44.4 699929000
Posterior Medial Right Neck Skin C44.4 699929000
Posterior Midline Right Neck Skin C44.4 699929000
Posterior Lateral Right Neck Skin C44.4 244105004
Anterior Lateral Right Nose Skin C44.3 244089006
Anterior Medial Right Nose Skin C44.3 244089006
Anterior Midline Right Nose Skin C44.3 314394005
Right Occipital Lymphoid Tissue C77.0 3916005
Right Occipital Bone C41.0 787062000
Right Ossa Coxae Bone C41.4 28254004
Right Ovary C56.9 20837000
Right Palatine Bone C41.0 51283005
Right Pancreas C25.9 64163001
Right Paraaortic Lymphoid Tissue C77.2 245285004
Right Parietal Bone C41.0 24924006
Right Parotid Lymphoid Tissue C77.0 85706002
Right Patella Bone C40.3 734210004
Right Pectoral Lymphoid Tissue C77.3 69691007
Right Peritracheal Lymphoid Tissue C77.1 127935009
Right Pisiform Bone C40.1 764706005
Right Popliteal Lymphoid Tissue C77.4 47471008
Right Porta Hepatis Lymphoid Tissue C77.2 61492009
Right Preauricular Lymphoid Tissue C77.0 25247006
Right Pubis Bone C41.4 734357000
Right Radius Bone C40.0 719465008
Right Retroperitoneal Lymphoid Tissue C77.2 91394001
Right Rib 1 Bone C41.3 48535007
Right Rib 10 Bone C41.3 77644006
Right Rib 11 Bone C41.3 58830002
Right Rib 12 Bone C41.3 43993008
Right Rib 2 Bone C41.3 78247007
Right Rib 3 Bone C41.3 25888004
Right Rib 4 Bone C41.3 25523003
Right Rib 5 Bone C41.3 15339008
Right Rib 6 Bone C41.3 59558009
Right Rib 7 Bone C41.3 24915002
Right Rib 8 Bone C41.3 5953002
Right Rib 9 Bone C41.3 22565002
Anterior Lateral Right Scalp Skin C44.4 699900002
Anterior Midline Right Scalp Skin C44.4 699900002
Anterior Medial Right Scalp Skin C44.4 699900002
Posterior Medial Right Scalp Skin C44.4 61719002
Posterior Midline Right Scalp Skin C44.4 61719002
Posterior Lateral Right Scalp Skin C44.4 61719002
Right Scaphoid Bone C40.1 724197000
Right Scapula Or Shoulder Blade Bone C40.0 719628000
Anterior Lateral Right Shoulder Skin C44.6 771102004
Anterior Midline Right Shoulder Skin C44.6 771102004
Anterior Medial Right Shoulder Skin C44.6 771102004
Posterior Medial Right Shoulder Skin C44.6 771102004
Posterior Midline Right Shoulder Skin C44.6 771102004
Posterior Lateral Right Shoulder Skin C44.6 771102004
Right Small Intestine C17.9 30315005
Right Sphenoid Bone C41.0 73117003
Right Spleen Lymphoid Tissue C42.2 78961009
Right Spleen C42.2 78961009
Right Splenic Hilar Lymphoid Tissue C77.2 280824006
Right Stapes Bone C30.1 22718006
Right Stomach C16.9 69695003
Right Submandibular Lymphoid Tissue C77.0 59503006
Right Submental Lymphoid Tissue C77.0 46055009
Right Supraclavicular Lymphoid Tissue C77.0 76838003
Right Talus Bone C40.3 737406006
Right Temporal Bone C41.0 763816004
Right Testis C62.9 15598003
Right Thymic Lymphoid Tissue C37.9 9875009
Right Tibia Bone C40.2 719491009
Right Tonsils Lymphoid Tissue C09.9 1721005
Right Trapezium Bone C40.1 764662000
Right Trapezoid Bone C40.1 787048007
Right Triquetral Bone C40.1 764824001
Right Ulna Bone C40.0 719463001
Anterior Lateral Right Upper Arm Skin C44.6 788804004
Anterior Midline Right Upper Arm Skin C44.6 788804004
Anterior Medial Right Upper Arm Skin C44.6 788804004
Posterior Medial Right Upper Arm Skin C44.6 788804004
Posterior Midline Right Upper Arm Skin C44.6 788804004
Posterior Lateral Right Upper Arm Skin C44.6 788804004
Anterior Lateral Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Anterior Midline Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Anterior Medial Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Posterior Medial Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Posterior Midline Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Posterior Lateral Right Upper Leg (Anterior And Posterior Thigh) Skin C44.7 774101005
Right Vomer Bone C41.0 87166008
Right Waldeyer Ring Lymphoid Tissue C14.2 17861009
Anterior Lateral Right Wrist Skin C44.6 244157004
Anterior Midline Right Wrist Skin C44.6 24527008
Anterior Medial Right Wrist Skin C44.6 24527008
Posterior Medial Right Wrist Skin C44.6 52876008
Posterior Midline Right Wrist Skin C44.6 52876008
Posterior Lateral Right Wrist Skin C44.6 244157004
Right Zygomatic Bone C41.0 787059003
Abdomen Skin C44.5 86381001
Abdominal Lymphoid Tissue C77.2 818991007
Adenoid Lymphoid Tissue C11.1 55940004
Anus C44.5 53505006
Back Skin C44.5 66643007
Bladder C67.9 89837001
Brain C71.9 12738006
Buttocks Skin C44.5 46862004
Celiac Lymphoid Tissue C77.2 47985009
Cerebrospinal Fluid C72.9 65216001
Cervical Vertebrae 1 Bone C41.2 14806007
Cervical Vertebrae 2 Bone C41.2 39976000
Cervical Vertebrae 3 Bone C41.2 113205007
Cervical Vertebrae 4 Bone C41.2 5329002
Cervical Vertebrae 5 Bone C41.2 36978003
Cervical Vertebrae 6 Bone C41.2 36054005
Cervical Vertebrae 7 Bone C41.2 87391001
Cervix C53.9 71252005
Chest Skin C44.5 74160004
Chin Skin C44.3 23747009
Esophagus C15.9 32849002
Forehead Skin C44.3 68698007
Gallbladder C23.9 28231008
Genitalia Skin C51.0, skin of vulva C51.9, skin of penis C60.9 and skin of scrotum C63.2 281679005
Heart C38.0 80891009
Hilar Lymphoid Tissue C77.1 53074004
Large Intestine C18.9 14742008
Leptomeningeal C70.9 66697007
Lingual Tonsils Lymphoid Tissue C02.4 2048000
Lip Skin C44.0 88089004
Liver C22.0 10200004
Lumbar Vertebrae 1 Bone C41.2 66794005
Lumbar Vertebrae 2 Bone C41.2 14293000
Lumbar Vertebrae 3 Bone C41.2 36470004
Lumbar Vertebrae 4 Bone C41.2 11994002
Lumbar Vertebrae 5 Bone C41.2 49668003
Mesenteric Lymphoid Tissue C77.2 279795009
Nasal Mucosa C30.0 34508005
Nasopharynx Lymphoid Tissue C11.1 55940004
Neck Skin C44.4 43081002
Posterior Neck Skin C44.4 4658004
Nose Skin C44.3 281714003
Oral Mucosa C06.9 113277000
Pancreas C25.9 15776009
Paraaortic Lymphoid Tissue C77.2 245285004
Porta Hepatis Lymphoid Tissue C77.2 61492009
Retroperitoneal Lymphoid Tissue C77.2 91394001
Scalp Skin C44.4 43067004
Posterior Scalp Skin C44.4 61719002
Small Intestine C17.9 30315005
Spinal Cord C72.0 2748008
Spleen Lymphoid Tissue C42.2 78961009
Stomach C16.9 69695003
Thoracic Vertebrae 1 Bone C41.2 64864005
Thoracic Vertebrae 10 Bone C41.2 7610001
Thoracic Vertebrae 11 Bone C41.2 12989004
Thoracic Vertebrae 12 Bone C41.2  23215003
Thoracic Vertebrae 2 Bone C41.2 53733008
Thoracic Vertebrae 3 Bone C41.2 1626008
Thoracic Vertebrae 4 Bone C41.2 73071006
Thoracic Vertebrae 5 Bone C41.2 56401006
Thoracic Vertebrae 6 Bone C41.2 45296009
Thoracic Vertebrae 7 Bone C41.2 62487009
Thoracic Vertebrae 8 Bone C41.2 11068009
Thoracic Vertebrae 9 Bone C41.2 82687006
Tonsils Lymphoid Tissue C09.9 91636008
Vagina C52.9 76784001
Waldeyer Ring Lymphoid Tissue C14.2 17861009

Conclusions

Structured capture of clinical tumor characteristics can can facilitate analysis of patient-level data and reduce time-to-analytics of RWD. Here we present the Lesion Information Instrument, a freely-available data collection instrument that can be readily integrated into an existing REDCAp® project. The LII captures over 150 clinical tumor characteristics data elements with the goal of enhancing the understanding of tumor biology and improving the lives of patients living with cancer.

License

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David Michael Miller
Medical Oncologist and Dermatologist

My research interests include clinical and translational research in advanced skin cancers.

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